Pattern of distant metastases in colorectal cancer: A SEER based study

Miaozhen Qiu, Jianming Hu, Dajun Yang, David Peter Cosgrove, Ruihua Xu

Research output: Contribution to journalArticle

Abstract

More and more evidences suggest that primary colon and rectum tumors should not be considered as a single disease entity. In this manuscript, we evaluate the metastatic patterns of colon and rectum cancers and analyze the potential distribution of metastatic disease in these two malignancies. Data queried for this analysis include colorectal adenocarcinoma (2010-2011) from the Surveillance, Epidemiology, and End Results Program (SEER) database. Metastatic distribution information was provided for liver, lung, bone and brain. All of statistical analyses were performed using the Intercooled Stata 13.0 (Stata Corporation, College Station, TX). All statistical tests were two-sided. Totally, there were 46,027 eligible patients for analysis. We found that colon cancer had a higher incident rate of liver metastasis than rectum cancer (13.8% vs 12.3%), while rectum cancer had a higher incident rate of lung (5.6% vs 3.7%) and bone (1.2% vs 0.8%) metastasis than colon cancer, P

Original languageEnglish (US)
Pages (from-to)38658-38666
Number of pages9
JournalOncotarget
Volume6
Issue number36
DOIs
StatePublished - 2015

Fingerprint

SEER Program
Rectal Neoplasms
Colonic Neoplasms
Colorectal Neoplasms
Neoplasm Metastasis
Bone and Bones
Lung
Information Dissemination
Liver
Rectum
Neoplasms
Colon
Adenocarcinoma
Databases
Brain

Keywords

  • Colon cancer
  • Incidence
  • Metastases
  • Rectal cancer
  • SEER

ASJC Scopus subject areas

  • Oncology

Cite this

Qiu, M., Hu, J., Yang, D., Cosgrove, D. P., & Xu, R. (2015). Pattern of distant metastases in colorectal cancer: A SEER based study. Oncotarget, 6(36), 38658-38666. https://doi.org/10.18632/oncotarget.6130

Pattern of distant metastases in colorectal cancer : A SEER based study. / Qiu, Miaozhen; Hu, Jianming; Yang, Dajun; Cosgrove, David Peter; Xu, Ruihua.

In: Oncotarget, Vol. 6, No. 36, 2015, p. 38658-38666.

Research output: Contribution to journalArticle

Qiu, M, Hu, J, Yang, D, Cosgrove, DP & Xu, R 2015, 'Pattern of distant metastases in colorectal cancer: A SEER based study', Oncotarget, vol. 6, no. 36, pp. 38658-38666. https://doi.org/10.18632/oncotarget.6130
Qiu, Miaozhen ; Hu, Jianming ; Yang, Dajun ; Cosgrove, David Peter ; Xu, Ruihua. / Pattern of distant metastases in colorectal cancer : A SEER based study. In: Oncotarget. 2015 ; Vol. 6, No. 36. pp. 38658-38666.
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