Interaktion von patient und ventilator während nichtinvasiver druckunterstützter spontanatmung bei patienten mit hyperkapnischer COPD

Translated title of the contribution: Patient-ventilator interaction with noninvasive pressure support ventilation in patients with hypercapnic COPD

W. Pankow, H. Becket, U. Köhler, Hartmut Schneider, T. Penzel, J. H. Peter

Research output: Contribution to journalArticle

Abstract

Background: Noninvasive pressure support ventilation (NPSV) demands triggering with each breath. This study investigates the effects of NPSV via face mask on breathing pattern, ventilation and respiratory muscle loading in patients with hypercapnic stable COPD. Methods: 7 patients (age 66 ± 9 years; FEV1 43 ± 13% predicted; PaO2 52 ± 19 mmHg; PaCO2 58 ± 12 mmHg) were included. The physiologic variables were evaluated during spontaneous breathing and at the end of a 60 minutes period with NPSV. Inspiratory positive airway pressure (IPAP) and expiratory positive airway pressure (EPAP) were adjusted to 12-14 cm H2O and 3 cm H2O, respectively. Respiratory muscle activity was measured as esophageal and transdiaphrgmatic pressure time product (PTPes and PTPdi). Results: Non-triggering was observed only occasionaly. Compared to unsupported spontaneous breathing NPSV improved ventilation: PaCO2 was reduced from 58 ± 11 mmHg to 50 ± 14 mmHg (p ± 0,05). Respiratory muscles were unloaded by 30% (p ± 0,05). Breathing frenquency and breathing pattern did not change. Conclusions: In patients with hypercapnic stable COPD NPSV effectively recognizes and supports breathing efforts. As a result ventilation is improved and respiratory muscles are unloaded.

Original languageGerman
Pages (from-to)7-12
Number of pages6
JournalPneumologie
Volume55
Issue number1
DOIs
StatePublished - 2001
Externally publishedYes

Fingerprint

Mechanical Ventilators
Chronic Obstructive Pulmonary Disease
Ventilation
Pressure
Respiration
Respiratory Muscles
Masks

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Interaktion von patient und ventilator während nichtinvasiver druckunterstützter spontanatmung bei patienten mit hyperkapnischer COPD. / Pankow, W.; Becket, H.; Köhler, U.; Schneider, Hartmut; Penzel, T.; Peter, J. H.

In: Pneumologie, Vol. 55, No. 1, 2001, p. 7-12.

Research output: Contribution to journalArticle

Pankow, W. ; Becket, H. ; Köhler, U. ; Schneider, Hartmut ; Penzel, T. ; Peter, J. H. / Interaktion von patient und ventilator während nichtinvasiver druckunterstützter spontanatmung bei patienten mit hyperkapnischer COPD. In: Pneumologie. 2001 ; Vol. 55, No. 1. pp. 7-12.
@article{b8c65e8ebdcc469580c8995b2304053e,
title = "Interaktion von patient und ventilator w{\"a}hrend nichtinvasiver druckunterst{\"u}tzter spontanatmung bei patienten mit hyperkapnischer COPD",
abstract = "Background: Noninvasive pressure support ventilation (NPSV) demands triggering with each breath. This study investigates the effects of NPSV via face mask on breathing pattern, ventilation and respiratory muscle loading in patients with hypercapnic stable COPD. Methods: 7 patients (age 66 ± 9 years; FEV1 43 ± 13{\%} predicted; PaO2 52 ± 19 mmHg; PaCO2 58 ± 12 mmHg) were included. The physiologic variables were evaluated during spontaneous breathing and at the end of a 60 minutes period with NPSV. Inspiratory positive airway pressure (IPAP) and expiratory positive airway pressure (EPAP) were adjusted to 12-14 cm H2O and 3 cm H2O, respectively. Respiratory muscle activity was measured as esophageal and transdiaphrgmatic pressure time product (PTPes and PTPdi). Results: Non-triggering was observed only occasionaly. Compared to unsupported spontaneous breathing NPSV improved ventilation: PaCO2 was reduced from 58 ± 11 mmHg to 50 ± 14 mmHg (p ± 0,05). Respiratory muscles were unloaded by 30{\%} (p ± 0,05). Breathing frenquency and breathing pattern did not change. Conclusions: In patients with hypercapnic stable COPD NPSV effectively recognizes and supports breathing efforts. As a result ventilation is improved and respiratory muscles are unloaded.",
author = "W. Pankow and H. Becket and U. K{\"o}hler and Hartmut Schneider and T. Penzel and Peter, {J. H.}",
year = "2001",
doi = "10.1055/s-2001-10445",
language = "German",
volume = "55",
pages = "7--12",
journal = "Pneumologie",
issn = "0934-8387",
publisher = "Georg Thieme Verlag",
number = "1",

}

TY - JOUR

T1 - Interaktion von patient und ventilator während nichtinvasiver druckunterstützter spontanatmung bei patienten mit hyperkapnischer COPD

AU - Pankow, W.

AU - Becket, H.

AU - Köhler, U.

AU - Schneider, Hartmut

AU - Penzel, T.

AU - Peter, J. H.

PY - 2001

Y1 - 2001

N2 - Background: Noninvasive pressure support ventilation (NPSV) demands triggering with each breath. This study investigates the effects of NPSV via face mask on breathing pattern, ventilation and respiratory muscle loading in patients with hypercapnic stable COPD. Methods: 7 patients (age 66 ± 9 years; FEV1 43 ± 13% predicted; PaO2 52 ± 19 mmHg; PaCO2 58 ± 12 mmHg) were included. The physiologic variables were evaluated during spontaneous breathing and at the end of a 60 minutes period with NPSV. Inspiratory positive airway pressure (IPAP) and expiratory positive airway pressure (EPAP) were adjusted to 12-14 cm H2O and 3 cm H2O, respectively. Respiratory muscle activity was measured as esophageal and transdiaphrgmatic pressure time product (PTPes and PTPdi). Results: Non-triggering was observed only occasionaly. Compared to unsupported spontaneous breathing NPSV improved ventilation: PaCO2 was reduced from 58 ± 11 mmHg to 50 ± 14 mmHg (p ± 0,05). Respiratory muscles were unloaded by 30% (p ± 0,05). Breathing frenquency and breathing pattern did not change. Conclusions: In patients with hypercapnic stable COPD NPSV effectively recognizes and supports breathing efforts. As a result ventilation is improved and respiratory muscles are unloaded.

AB - Background: Noninvasive pressure support ventilation (NPSV) demands triggering with each breath. This study investigates the effects of NPSV via face mask on breathing pattern, ventilation and respiratory muscle loading in patients with hypercapnic stable COPD. Methods: 7 patients (age 66 ± 9 years; FEV1 43 ± 13% predicted; PaO2 52 ± 19 mmHg; PaCO2 58 ± 12 mmHg) were included. The physiologic variables were evaluated during spontaneous breathing and at the end of a 60 minutes period with NPSV. Inspiratory positive airway pressure (IPAP) and expiratory positive airway pressure (EPAP) were adjusted to 12-14 cm H2O and 3 cm H2O, respectively. Respiratory muscle activity was measured as esophageal and transdiaphrgmatic pressure time product (PTPes and PTPdi). Results: Non-triggering was observed only occasionaly. Compared to unsupported spontaneous breathing NPSV improved ventilation: PaCO2 was reduced from 58 ± 11 mmHg to 50 ± 14 mmHg (p ± 0,05). Respiratory muscles were unloaded by 30% (p ± 0,05). Breathing frenquency and breathing pattern did not change. Conclusions: In patients with hypercapnic stable COPD NPSV effectively recognizes and supports breathing efforts. As a result ventilation is improved and respiratory muscles are unloaded.

UR - http://www.scopus.com/inward/record.url?scp=0035133030&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035133030&partnerID=8YFLogxK

U2 - 10.1055/s-2001-10445

DO - 10.1055/s-2001-10445

M3 - Article

C2 - 11236359

AN - SCOPUS:0035133030

VL - 55

SP - 7

EP - 12

JO - Pneumologie

JF - Pneumologie

SN - 0934-8387

IS - 1

ER -