Patient-specific finite element modeling for femoral bone augmentation

Ehsan Basafa; Robert S. Armiger; Michael D. Kutzer; Stephen M Belkoff; Simon C Mears; Mehran Armand

doi:10.1016/j.medengphy.2013.01.003

Patient-specific finite element modeling for femoral bone augmentation

Ehsan Basafa, Robert S. Armiger, Michael D. Kutzer, Stephen M Belkoff, Simon C Mears, Mehran Armand

School of Medicine

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

The aim of this study was to provide a fast and accurate finite element (FE) modeling scheme for predicting bone stiffness and strength suitable for use within the framework of a computer-assisted osteoporotic femoral bone augmentation surgery system. The key parts of the system, i.e. preoperative planning and intraoperative assessment of the augmentation, demand the finite element model to be solved and analyzed rapidly. Available CT scans and mechanical testing results from nine pairs of osteoporotic femur bones, with one specimen from each pair augmented by polymethylmethacrylate (PMMA) bone cement, were used to create FE models and compare the results with experiments. Correlation values of R² = 0.72-0.95 were observed between the experiments and FEA results which, combined with the fast model convergence (~3 min for ~250,000 degrees of freedom), makes the presented modeling approach a promising candidate for the intended application of preoperative planning and intraoperative assessment of bone augmentation surgery.

Original language	English (US)
Pages (from-to)	860-865
Number of pages	6
Journal	Medical Engineering and Physics
Volume	35
Issue number	6
DOIs	https://doi.org/10.1016/j.medengphy.2013.01.003
State	Published - 2013

Keywords

Biomechanics
Bone cement
Femoroplasty
Finite element analysis

ASJC Scopus subject areas

Biophysics
Biomedical Engineering

Access to Document

10.1016/j.medengphy.2013.01.003

Cite this

@article{9ba5abe2c33b4d9e916f49416a62ec7c,

title = "Patient-specific finite element modeling for femoral bone augmentation",

abstract = "The aim of this study was to provide a fast and accurate finite element (FE) modeling scheme for predicting bone stiffness and strength suitable for use within the framework of a computer-assisted osteoporotic femoral bone augmentation surgery system. The key parts of the system, i.e. preoperative planning and intraoperative assessment of the augmentation, demand the finite element model to be solved and analyzed rapidly. Available CT scans and mechanical testing results from nine pairs of osteoporotic femur bones, with one specimen from each pair augmented by polymethylmethacrylate (PMMA) bone cement, were used to create FE models and compare the results with experiments. Correlation values of R2 = 0.72-0.95 were observed between the experiments and FEA results which, combined with the fast model convergence (~3 min for ~250,000 degrees of freedom), makes the presented modeling approach a promising candidate for the intended application of preoperative planning and intraoperative assessment of bone augmentation surgery.",

keywords = "Biomechanics, Bone cement, Femoroplasty, Finite element analysis",

author = "Ehsan Basafa and Armiger, {Robert S.} and Kutzer, {Michael D.} and Belkoff, {Stephen M} and Mears, {Simon C} and Mehran Armand",

note = "Funding Information: Grant no. 5 R21 EB0077747-03 from National Institutes of Health (NIH/NIBIB) . The funding source did not have any involvement in the study design, in the collection, analysis and interpretation of data, in the writing of the manuscript, or in the decision to submit this manuscript for publication. Funding Information: We would like to thank Edward G. Sutter for providing us with the experimental data and his insights about interpreting those data. This work was supported by grant no. 5 R21 EB0077747-03 from National Institutes of Health (NIH/NIBIB).",

year = "2013",

doi = "10.1016/j.medengphy.2013.01.003",

language = "English (US)",

volume = "35",

pages = "860--865",

journal = "Medical Engineering and Physics",

issn = "1350-4533",

publisher = "Elsevier BV",

number = "6",

}

TY - JOUR

T1 - Patient-specific finite element modeling for femoral bone augmentation

AU - Basafa, Ehsan

AU - Armiger, Robert S.

AU - Kutzer, Michael D.

AU - Belkoff, Stephen M

AU - Mears, Simon C

AU - Armand, Mehran

N1 - Funding Information: Grant no. 5 R21 EB0077747-03 from National Institutes of Health (NIH/NIBIB) . The funding source did not have any involvement in the study design, in the collection, analysis and interpretation of data, in the writing of the manuscript, or in the decision to submit this manuscript for publication. Funding Information: We would like to thank Edward G. Sutter for providing us with the experimental data and his insights about interpreting those data. This work was supported by grant no. 5 R21 EB0077747-03 from National Institutes of Health (NIH/NIBIB).

PY - 2013

Y1 - 2013

N2 - The aim of this study was to provide a fast and accurate finite element (FE) modeling scheme for predicting bone stiffness and strength suitable for use within the framework of a computer-assisted osteoporotic femoral bone augmentation surgery system. The key parts of the system, i.e. preoperative planning and intraoperative assessment of the augmentation, demand the finite element model to be solved and analyzed rapidly. Available CT scans and mechanical testing results from nine pairs of osteoporotic femur bones, with one specimen from each pair augmented by polymethylmethacrylate (PMMA) bone cement, were used to create FE models and compare the results with experiments. Correlation values of R2 = 0.72-0.95 were observed between the experiments and FEA results which, combined with the fast model convergence (~3 min for ~250,000 degrees of freedom), makes the presented modeling approach a promising candidate for the intended application of preoperative planning and intraoperative assessment of bone augmentation surgery.

AB - The aim of this study was to provide a fast and accurate finite element (FE) modeling scheme for predicting bone stiffness and strength suitable for use within the framework of a computer-assisted osteoporotic femoral bone augmentation surgery system. The key parts of the system, i.e. preoperative planning and intraoperative assessment of the augmentation, demand the finite element model to be solved and analyzed rapidly. Available CT scans and mechanical testing results from nine pairs of osteoporotic femur bones, with one specimen from each pair augmented by polymethylmethacrylate (PMMA) bone cement, were used to create FE models and compare the results with experiments. Correlation values of R2 = 0.72-0.95 were observed between the experiments and FEA results which, combined with the fast model convergence (~3 min for ~250,000 degrees of freedom), makes the presented modeling approach a promising candidate for the intended application of preoperative planning and intraoperative assessment of bone augmentation surgery.

KW - Biomechanics

KW - Bone cement

KW - Femoroplasty

KW - Finite element analysis

UR - http://www.scopus.com/inward/record.url?scp=84890856814&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84890856814&partnerID=8YFLogxK

U2 - 10.1016/j.medengphy.2013.01.003

DO - 10.1016/j.medengphy.2013.01.003

M3 - Article

C2 - 23375663

AN - SCOPUS:84890856814

SN - 1350-4533

VL - 35

SP - 860

EP - 865

JO - Medical Engineering and Physics

JF - Medical Engineering and Physics

IS - 6

ER -

Patient-specific finite element modeling for femoral bone augmentation

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this