Patient specific computerized phantoms to estimate dose in pediatric CT

W. P. Segars, G. Sturgeon, X. Li, L. Cheng, C. Ceritoglu, J. T. Ratnanather, M. I. Miller, B. M.W. Tsui, D. Frush, E. Samei

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We create a series of detailed computerized phantoms to estimate patient organ and effective dose in pediatric CT and investigate techniques for efficiently creating patient-specific phantoms based on imaging data. The initial anatomy of each phantom was previously developed based on manual segmentation of pediatric CT data. Each phantom was extended to include a more detailed anatomy based on morphing an existing adult phantom in our laboratory to match the framework (based on segmentation) defined for the target pediatric model. By morphing a template anatomy to match the patient data in the LDDMM framework, it was possible to create a patient specific phantom with many anatomical structures, some not visible in the CT data. The adult models contain thousands of defined structures that were transformed to define them in each pediatric anatomy. The accuracy of this method, under different conditions, was tested using a known voxelized phantom as the target. Errors were measured in terms of a distance map between the predicted organ surfaces and the known ones. We also compared calculated dose measurements to see the effect of different magnitudes of errors in morphing. Despite some variations in organ geometry, dose measurements from morphing predictions were found to agree with those calculated from the voxelized phantom thus demonstrating the feasibility of our methods.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2009
Subtitle of host publicationPhysics of Medical Imaging
DOIs
StatePublished - Jun 16 2009
EventMedical Imaging 2009: Physics of Medical Imaging - Lake Buena Vista, FL, United States
Duration: Feb 9 2009Feb 12 2009

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7258
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2009: Physics of Medical Imaging
CountryUnited States
CityLake Buena Vista, FL
Period2/9/092/12/09

Keywords

  • CT
  • Computerized phantoms
  • Dose
  • Pediatric

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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  • Cite this

    Segars, W. P., Sturgeon, G., Li, X., Cheng, L., Ceritoglu, C., Ratnanather, J. T., Miller, M. I., Tsui, B. M. W., Frush, D., & Samei, E. (2009). Patient specific computerized phantoms to estimate dose in pediatric CT. In Medical Imaging 2009: Physics of Medical Imaging [72580H] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 7258). https://doi.org/10.1117/12.813517