Patient-Reported Impact of Pelvic Organ Prolapse on Continence and Sexual Function in Women with Exstrophy-Epispadias Complex

Ross G. Everett, Kathy M. Lue, Sunil S. Reddy, Daniel A. Friedlander, Cameron E. Alexander, Ezekiel E. Young, Mahmoud Abdelwahab, Nilay M. Gandhi, Edward James Wright, John Phillip Gearhart

Research output: Contribution to journalArticle

Abstract

Objective This study aimed to characterize long-term urogynecologic issues of women with a history of bladder exstrophy and pelvic organ prolapse (POP) and to assess the impact of POP repair on continence and sexual function. Design Patient demographics and surgical history related to exstrophy and POP were collected through chart review. Patient perceptions regarding sexual function, urinary continence, and quality of life were assessed through Web-based administration of validated questionnaires: International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form and POP-Urinary Incontinence Sexual Questionnaire. Setting Maryland, United States. Participants Review of a single-institution exstrophy-epispadias complex database resulted in 25 adult female patients with a history of POP treated at the authors' institution. Eleven patients participated and were included in the analysis. Main Outcome Measures Urinary continence and sexual function. Results All participants underwent surgical repair for prolapse, with 7 (63.6%) experiencing unsuccessful initial repair and subsequent recurrence. Median total number of POP repairs was 2.5 (1-4). After correction of POP, patients reported a median improvement in International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form scores of 11 (21 to -1) of 21 and in POP-Urinary Incontinence Sexual Questionnaire scores of 9.5 (6.5-33.0) of 48.0. With regard to urinary continence, 6 (54.5%) patients presently reported no incontinence, 3 (27.3%) reported mild incontinence, and 2 (18.2%) reported continuous incontinence. Conclusions Pelvic organ prolapse poses significant reductions in quality of life for women born with exstrophy, with effects on urinary continence and sexual function. Identification and correction of prolapse seems to result in notable improvements in the lives of these patients.

Original languageEnglish (US)
Pages (from-to)377-381
Number of pages5
JournalFemale Pelvic Medicine and Reconstructive Surgery
Volume23
Issue number6
DOIs
StatePublished - Nov 1 2017

Keywords

  • bladder exstrophy
  • pelvic organ prolapse
  • sexual dysfunction
  • urinary incontinence

ASJC Scopus subject areas

  • Surgery
  • Obstetrics and Gynecology
  • Urology

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