Patient preferences for coronary CT angiography with stress perfusion, SPECT, or invasive coronary angiography

Anum Minhas, Marc Dewey, Andrea L. Vavere, Yutaka Tanami, Mohammad R. Ostovaneh, Michael Laule, Carlos E. Rochitte, Hiroyuki Niinuma, Klaus F. Kofoed, Jacob Geleijns, John Hoe, Marcus Y. Chen, Kakuya Kitagawa, Cesar Nomura, Melvin E. Clouse, Frank J. Rybicki, Swee Yaw Tan, Narinder Paul, Matthew Matheson, Christopher CoxMatthias Rief, Pia Maier, Sarah Feger, Michail Plotkin, Eva Schönenberger

Research output: Contribution to journalArticle

Abstract

Background: Patient preference is pivotal for widespread adoption of tests in clinical practice. Patient preferences for invasive versus other noninvasive tests for coronary artery disease are not known. Purpose: To compare patient acceptance and preferences for noninvasive and invasive cardiac imaging in North and South America, Asia, and Europe. Materials and Methods: This was a prospective 16-center trial in 381 study participants undergoing coronary CT angiography with stress perfusion, SPECT, and invasive coronary angiography (ICA). Patient preferences were collected by using a previously validated questionnaire translated into eight languages. Responses were converted to ordinal scales and were modeled with generalized linear mixed models. Results: In patients in whom at least one test was associated with pain, CT and SPECT showed reduced median pain levels, reported on 0-100 visual analog scales, from 20 for ICA (interquartile range [IQR], 4-50) to 6 for CT (IQR, 0-27.5) and 5 for SPECT (IQR, 0-25) (P , .001). Patients from Asia reported significantly more pain than patients from other continents for ICA (median, 25; IQR, 10-50; P = .01), CT (median, 10; IQR, 0-30; P = .02), and SPECT (median, 7; IQR, 0-28; P = .03). Satisfaction with preparation differed by continent and test (P = .01), with patients from Asia reporting generally lower ratings. Patients from North America had greater percentages of "very high" or "high" satisfaction than patients from other continents for ICA (96% vs 82%, respectively; P , .001) and SPECT (95% vs 79%, respectively; P = .04) but not for CT (89% vs 86%, respectively; P = .70). Among all patients, CT was preferred by 54% of patients, compared with 18% for SPECT and 28% for ICA (P , .001). Conclusion: For cardiac imaging, patients generally favored CT angiography with stress perfusion, while study participants from Asia generally reported lowest satisfaction.

Original languageEnglish (US)
Pages (from-to)340-348
Number of pages9
JournalRadiology
Volume291
Issue number2
DOIs
StatePublished - May 1 2019

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Patient Preference
Single-Photon Emission-Computed Tomography
Coronary Angiography
Perfusion
North America
Pain
Computed Tomography Angiography
South America
Visual Analog Scale
Patient Satisfaction
Coronary Artery Disease
Linear Models
Language

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Minhas, A., Dewey, M., Vavere, A. L., Tanami, Y., Ostovaneh, M. R., Laule, M., ... Schönenberger, E. (2019). Patient preferences for coronary CT angiography with stress perfusion, SPECT, or invasive coronary angiography. Radiology, 291(2), 340-348. https://doi.org/10.1148/radiol.2019181409

Patient preferences for coronary CT angiography with stress perfusion, SPECT, or invasive coronary angiography. / Minhas, Anum; Dewey, Marc; Vavere, Andrea L.; Tanami, Yutaka; Ostovaneh, Mohammad R.; Laule, Michael; Rochitte, Carlos E.; Niinuma, Hiroyuki; Kofoed, Klaus F.; Geleijns, Jacob; Hoe, John; Chen, Marcus Y.; Kitagawa, Kakuya; Nomura, Cesar; Clouse, Melvin E.; Rybicki, Frank J.; Tan, Swee Yaw; Paul, Narinder; Matheson, Matthew; Cox, Christopher; Rief, Matthias; Maier, Pia; Feger, Sarah; Plotkin, Michail; Schönenberger, Eva.

In: Radiology, Vol. 291, No. 2, 01.05.2019, p. 340-348.

Research output: Contribution to journalArticle

Minhas, A, Dewey, M, Vavere, AL, Tanami, Y, Ostovaneh, MR, Laule, M, Rochitte, CE, Niinuma, H, Kofoed, KF, Geleijns, J, Hoe, J, Chen, MY, Kitagawa, K, Nomura, C, Clouse, ME, Rybicki, FJ, Tan, SY, Paul, N, Matheson, M, Cox, C, Rief, M, Maier, P, Feger, S, Plotkin, M & Schönenberger, E 2019, 'Patient preferences for coronary CT angiography with stress perfusion, SPECT, or invasive coronary angiography', Radiology, vol. 291, no. 2, pp. 340-348. https://doi.org/10.1148/radiol.2019181409
Minhas, Anum ; Dewey, Marc ; Vavere, Andrea L. ; Tanami, Yutaka ; Ostovaneh, Mohammad R. ; Laule, Michael ; Rochitte, Carlos E. ; Niinuma, Hiroyuki ; Kofoed, Klaus F. ; Geleijns, Jacob ; Hoe, John ; Chen, Marcus Y. ; Kitagawa, Kakuya ; Nomura, Cesar ; Clouse, Melvin E. ; Rybicki, Frank J. ; Tan, Swee Yaw ; Paul, Narinder ; Matheson, Matthew ; Cox, Christopher ; Rief, Matthias ; Maier, Pia ; Feger, Sarah ; Plotkin, Michail ; Schönenberger, Eva. / Patient preferences for coronary CT angiography with stress perfusion, SPECT, or invasive coronary angiography. In: Radiology. 2019 ; Vol. 291, No. 2. pp. 340-348.
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T1 - Patient preferences for coronary CT angiography with stress perfusion, SPECT, or invasive coronary angiography

AU - Minhas, Anum

AU - Dewey, Marc

AU - Vavere, Andrea L.

AU - Tanami, Yutaka

AU - Ostovaneh, Mohammad R.

AU - Laule, Michael

AU - Rochitte, Carlos E.

AU - Niinuma, Hiroyuki

AU - Kofoed, Klaus F.

AU - Geleijns, Jacob

AU - Hoe, John

AU - Chen, Marcus Y.

AU - Kitagawa, Kakuya

AU - Nomura, Cesar

AU - Clouse, Melvin E.

AU - Rybicki, Frank J.

AU - Tan, Swee Yaw

AU - Paul, Narinder

AU - Matheson, Matthew

AU - Cox, Christopher

AU - Rief, Matthias

AU - Maier, Pia

AU - Feger, Sarah

AU - Plotkin, Michail

AU - Schönenberger, Eva

PY - 2019/5/1

Y1 - 2019/5/1

N2 - Background: Patient preference is pivotal for widespread adoption of tests in clinical practice. Patient preferences for invasive versus other noninvasive tests for coronary artery disease are not known. Purpose: To compare patient acceptance and preferences for noninvasive and invasive cardiac imaging in North and South America, Asia, and Europe. Materials and Methods: This was a prospective 16-center trial in 381 study participants undergoing coronary CT angiography with stress perfusion, SPECT, and invasive coronary angiography (ICA). Patient preferences were collected by using a previously validated questionnaire translated into eight languages. Responses were converted to ordinal scales and were modeled with generalized linear mixed models. Results: In patients in whom at least one test was associated with pain, CT and SPECT showed reduced median pain levels, reported on 0-100 visual analog scales, from 20 for ICA (interquartile range [IQR], 4-50) to 6 for CT (IQR, 0-27.5) and 5 for SPECT (IQR, 0-25) (P , .001). Patients from Asia reported significantly more pain than patients from other continents for ICA (median, 25; IQR, 10-50; P = .01), CT (median, 10; IQR, 0-30; P = .02), and SPECT (median, 7; IQR, 0-28; P = .03). Satisfaction with preparation differed by continent and test (P = .01), with patients from Asia reporting generally lower ratings. Patients from North America had greater percentages of "very high" or "high" satisfaction than patients from other continents for ICA (96% vs 82%, respectively; P , .001) and SPECT (95% vs 79%, respectively; P = .04) but not for CT (89% vs 86%, respectively; P = .70). Among all patients, CT was preferred by 54% of patients, compared with 18% for SPECT and 28% for ICA (P , .001). Conclusion: For cardiac imaging, patients generally favored CT angiography with stress perfusion, while study participants from Asia generally reported lowest satisfaction.

AB - Background: Patient preference is pivotal for widespread adoption of tests in clinical practice. Patient preferences for invasive versus other noninvasive tests for coronary artery disease are not known. Purpose: To compare patient acceptance and preferences for noninvasive and invasive cardiac imaging in North and South America, Asia, and Europe. Materials and Methods: This was a prospective 16-center trial in 381 study participants undergoing coronary CT angiography with stress perfusion, SPECT, and invasive coronary angiography (ICA). Patient preferences were collected by using a previously validated questionnaire translated into eight languages. Responses were converted to ordinal scales and were modeled with generalized linear mixed models. Results: In patients in whom at least one test was associated with pain, CT and SPECT showed reduced median pain levels, reported on 0-100 visual analog scales, from 20 for ICA (interquartile range [IQR], 4-50) to 6 for CT (IQR, 0-27.5) and 5 for SPECT (IQR, 0-25) (P , .001). Patients from Asia reported significantly more pain than patients from other continents for ICA (median, 25; IQR, 10-50; P = .01), CT (median, 10; IQR, 0-30; P = .02), and SPECT (median, 7; IQR, 0-28; P = .03). Satisfaction with preparation differed by continent and test (P = .01), with patients from Asia reporting generally lower ratings. Patients from North America had greater percentages of "very high" or "high" satisfaction than patients from other continents for ICA (96% vs 82%, respectively; P , .001) and SPECT (95% vs 79%, respectively; P = .04) but not for CT (89% vs 86%, respectively; P = .70). Among all patients, CT was preferred by 54% of patients, compared with 18% for SPECT and 28% for ICA (P , .001). Conclusion: For cardiac imaging, patients generally favored CT angiography with stress perfusion, while study participants from Asia generally reported lowest satisfaction.

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