Patient navigation significantly reduces delays in breast cancer diagnosis in the District of Columbia

Heather J. Hoffman, Nancy L. LaVerda, Heather A. Young, Paul H. Levine, Lisa M. Alexander, Rachel Brem, Larisa Caicedo, Jennifer Eng-Wong, Wayne Frederick, William Funderburk, Elmer Huerta, Sandra Swain, Steven R. Patierno

Research output: Contribution to journalArticle

Abstract

Background: Patient Navigation (PN) originated in Harlem as an intervention to help poor women overcome access barriers to timely breast cancer treatment. Despite rapid, nationally widespread adoption of PN, empirical evidence on its effectiveness is lacking. In 2005, National Cancer Institute initiated a multicenter PN Research Program (PNRP) to measure PN effectiveness for several cancers. The George Washington Cancer Institute, a project participant, established District of Columbia (DC)-PNRP to determine PN's ability to reduce breast cancer diagnostic time (number of days from abnormal screening to definitive diagnosis). Methods: A total of 2,601 women (1,047 navigated; 1,554 concurrent records-based nonnavigated) were examined for breast cancer from 2006 to 2010 at 9 hospitals/clinics in DC. Analyses included only women who reached complete diagnostic resolution. Differences in diagnostic time between navigation groups were tested with ANOVA models including categorical demographic and treatment variables. Log transformations normalized diagnostic time. Geometric means were estimated and compared using Tukey-Kramer P value adjustments. Results: Average - geometric mean [95% confidence interval (CI)] - diagnostic time (days) was significantly shorter for navigated, 25.1 (21.7, 29.0), than nonnavigated women, 42.1 (35.8, 49.6). Subanalyses revealed significantly shorter average diagnostic time for biopsied navigated women, 26.6 (21.8, 32.5) than biopsied nonnavigated women, 57.5 (46.3, 71.5). Amongnonbiopsied women, diagnostic time was shorter for navigated, 27.2 (22.8, 32.4), than nonnavigated women, 34.9 (29.2, 41.7), but not statistically significant. Conclusions: Navigated women, especially those requiring biopsy, reached their diagnostic resolution significantly faster than nonnavigated women. Impact: Results support previous findings of PN's positive influence on health care. PN should be a reimbursable expense to assure continuation of PN programs.

Original languageEnglish (US)
Pages (from-to)1655-1663
Number of pages9
JournalCancer Epidemiology Biomarkers and Prevention
Volume21
Issue number10
DOIs
StatePublished - Oct 2012

ASJC Scopus subject areas

  • Epidemiology
  • Oncology

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    Hoffman, H. J., LaVerda, N. L., Young, H. A., Levine, P. H., Alexander, L. M., Brem, R., Caicedo, L., Eng-Wong, J., Frederick, W., Funderburk, W., Huerta, E., Swain, S., & Patierno, S. R. (2012). Patient navigation significantly reduces delays in breast cancer diagnosis in the District of Columbia. Cancer Epidemiology Biomarkers and Prevention, 21(10), 1655-1663. https://doi.org/10.1158/1055-9965.EPI-12-0479