Pathways towards and away from Alzheimer's disease

Mark P. Mattson

Research output: Contribution to journalArticle

Abstract

Slowly but surely, Alzheimer's disease (AD) patients lose their memory and their cognitive abilities, and even their personalities may change dramatically. These changes are due to the progressive dysfunction and death of nerve cells that are responsible for the storage and processing of information. Although drugs can temporarily improve memory, at present there are no treatments that can stop or reverse the inexorable neurodegenerative process. But rapid progress towards understanding the cellular and molecular alterations that are responsible for the neuron's demise may soon help in developing effective preventative and therapeutic strategies.

Original languageEnglish (US)
Pages (from-to)631-639
Number of pages9
JournalNature
Volume430
Issue number7000
DOIs
StatePublished - Aug 5 2004

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