Pathways towards and away from Alzheimer's disease

Mark P. Mattson

doi:10.1038/nature02621

Pathways towards and away from Alzheimer's disease

Mark P. Mattson

School of Medicine

Research output: Contribution to journal › Article › peer-review

2260 Scopus citations

Abstract

Slowly but surely, Alzheimer's disease (AD) patients lose their memory and their cognitive abilities, and even their personalities may change dramatically. These changes are due to the progressive dysfunction and death of nerve cells that are responsible for the storage and processing of information. Although drugs can temporarily improve memory, at present there are no treatments that can stop or reverse the inexorable neurodegenerative process. But rapid progress towards understanding the cellular and molecular alterations that are responsible for the neuron's demise may soon help in developing effective preventative and therapeutic strategies.

Original language	English (US)
Pages (from-to)	631-639
Number of pages	9
Journal	Nature
Volume	430
Issue number	7000
DOIs	https://doi.org/10.1038/nature02621
State	Published - Aug 5 2004

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Pathways towards and away from Alzheimer's disease

Abstract

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