Pathways from sexual stigma to incident HIV and sexually transmitted infections among Nigerian MSM

Cristina Rodriguez-Hart, Rebecca G. Nowak, Rashelle Jean Musci, Danielle German, Ifeanyi Orazulike, Blessing Kayode, Hongjie Liu, Oye Gureje, Trevor A. Crowell, Stefan Baral, Man Charurat

Research output: Contribution to journalArticle

Abstract

Objectives: Sexual stigma affecting MSM in Nigeria may be an important driver of HIV and other sexually transmitted infections (STIs), but potential mechanisms through which this occurs are not well understood. This study assessed the contributions of suicidal ideation and sexual risk behaviors to causal pathways between stigma and HIV/STIs. Design: Data were collected from the TRUST/RV368 Study, a prospective cohort of 1480 MSM from Abuja and Lagos, Nigeria. Methods: Participants enrolled from March 2013 to February 2016 were classified into three stigma subgroups based on a latent class analysis of nine stigma indicators. Path analysis was used to test a model where disclosure led to stigma, then suicidal ideation, then condomless sex with casual sex partners, and finally incident HIV infection and/or newly diagnosed STIs, adjusting the model for age, education, having had female sex partners in the past 12 months, and sex position. Both direct and indirect (mediational) paths were tested for significance and analyses were clustered by city. Results: As stigma increased in severity, the proportion of incident HIV/STI infections increased in a dose-response relationship (low: 10.6%, medium: 14.2%, high 19.0%, P=0.008). All direct relationships in the model were significant and suicidal ideation and condomless sex partially mediated the association between stigma and incident HIV/STI infection. Conclusion: These findings highlight the importance of the meaningful integration of stigma-mitigation strategies in conjunction with mental health services as part of a broader strategy to reduce STI and HIV acquisitions among Nigerian MSM.

Original languageEnglish (US)
Pages (from-to)2415-2420
Number of pages6
JournalAIDS
Volume31
Issue number17
DOIs
StatePublished - Nov 13 2017

Fingerprint

Sexually Transmitted Diseases
HIV
Suicidal Ideation
Nigeria
Disclosure
Mental Health Services
Risk-Taking
Infection
Sexual Behavior
HIV Infections
Prospective Studies
Education

Keywords

  • HIV infections
  • incidence
  • MSM
  • path analysis
  • sexually transmitted infections
  • stigma

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

Cite this

Pathways from sexual stigma to incident HIV and sexually transmitted infections among Nigerian MSM. / Rodriguez-Hart, Cristina; Nowak, Rebecca G.; Musci, Rashelle Jean; German, Danielle; Orazulike, Ifeanyi; Kayode, Blessing; Liu, Hongjie; Gureje, Oye; Crowell, Trevor A.; Baral, Stefan; Charurat, Man.

In: AIDS, Vol. 31, No. 17, 13.11.2017, p. 2415-2420.

Research output: Contribution to journalArticle

Rodriguez-Hart, C, Nowak, RG, Musci, RJ, German, D, Orazulike, I, Kayode, B, Liu, H, Gureje, O, Crowell, TA, Baral, S & Charurat, M 2017, 'Pathways from sexual stigma to incident HIV and sexually transmitted infections among Nigerian MSM', AIDS, vol. 31, no. 17, pp. 2415-2420. https://doi.org/10.1097/QAD.0000000000001637
Rodriguez-Hart, Cristina ; Nowak, Rebecca G. ; Musci, Rashelle Jean ; German, Danielle ; Orazulike, Ifeanyi ; Kayode, Blessing ; Liu, Hongjie ; Gureje, Oye ; Crowell, Trevor A. ; Baral, Stefan ; Charurat, Man. / Pathways from sexual stigma to incident HIV and sexually transmitted infections among Nigerian MSM. In: AIDS. 2017 ; Vol. 31, No. 17. pp. 2415-2420.
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abstract = "Objectives: Sexual stigma affecting MSM in Nigeria may be an important driver of HIV and other sexually transmitted infections (STIs), but potential mechanisms through which this occurs are not well understood. This study assessed the contributions of suicidal ideation and sexual risk behaviors to causal pathways between stigma and HIV/STIs. Design: Data were collected from the TRUST/RV368 Study, a prospective cohort of 1480 MSM from Abuja and Lagos, Nigeria. Methods: Participants enrolled from March 2013 to February 2016 were classified into three stigma subgroups based on a latent class analysis of nine stigma indicators. Path analysis was used to test a model where disclosure led to stigma, then suicidal ideation, then condomless sex with casual sex partners, and finally incident HIV infection and/or newly diagnosed STIs, adjusting the model for age, education, having had female sex partners in the past 12 months, and sex position. Both direct and indirect (mediational) paths were tested for significance and analyses were clustered by city. Results: As stigma increased in severity, the proportion of incident HIV/STI infections increased in a dose-response relationship (low: 10.6{\%}, medium: 14.2{\%}, high 19.0{\%}, P=0.008). All direct relationships in the model were significant and suicidal ideation and condomless sex partially mediated the association between stigma and incident HIV/STI infection. Conclusion: These findings highlight the importance of the meaningful integration of stigma-mitigation strategies in conjunction with mental health services as part of a broader strategy to reduce STI and HIV acquisitions among Nigerian MSM.",
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AU - Kayode, Blessing

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