Pathology of a lepromatous eye

Gigi J. Ebenezer, Ebenezer Daniel

Research output: Contribution to journalArticle

Abstract

Histopathological examination of an enucleated eye from a lepromatous leprosy patient showed the cornea, ciliary body, and part of the choroid to be infiltrated by macrophages filled with Mycobacterium leprae. The walls of blood vessels in the sclera, ciliary body and the anterior choroid demonstrated the presence of M. leprae, giving credence to the blood-borne entry of M. leprae into the eye. Unlike the eyes of experimental animals infected with M. leprae, histopathological study of this eye from a lepromatous leprosy patient demonstrated that M. leprae, although demonstrable in the anterior choroid, could not be found in the posterior parts of the eye, substantiating the claim that leprosy does not affect the posterior parts of the eye directly.

Original languageEnglish (US)
Pages (from-to)23-26
Number of pages4
JournalInternational Journal of Leprosy and Other Mycobacterial Diseases
Volume68
Issue number1
StatePublished - Mar 1 2000
Externally publishedYes

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ASJC Scopus subject areas

  • Dermatology

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