Pathological gambling

Relation of skin conductance response to dopaminergic neurotransmission and sensation-seeking

Ericka Peterson, Arne Møller, Doris J. Doudet, Christopher J. Bailey, Kim Vang Hansen, Anders Rodell, Jakob Linnet, Albert Gjedde

Research output: Contribution to journalArticle

Abstract

Absent Skin Conductance Response (SCR) in pathological gambling (PG) may relate to dopaminergic mechanisms. We recruited equal numbers of PG subjects and healthy control (HC) subjects, and then tested the claim that SCR is less conditioned by dopaminergic activity in PG subjects. During active gambling, SCR differed in PG and HC subjects (PND) in high compared to normal sensation seekers. In both groups, PG and HC, highly sensation-seeking subjects had significant increase of receptor availability in striatum, compared to normally sensation-seeking subjects, separately (P

Original languageEnglish (US)
Pages (from-to)766-775
Number of pages10
JournalEuropean Neuropsychopharmacology
Volume20
Issue number11
DOIs
StatePublished - Nov 2010
Externally publishedYes

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Gambling
Synaptic Transmission
Skin
Healthy Volunteers

Keywords

  • Decision making
  • Dopamine
  • Pathological gambling
  • Positron emission tomography
  • Sensation seeking

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health
  • Pharmacology (medical)
  • Biological Psychiatry
  • Neurology
  • Pharmacology

Cite this

Pathological gambling : Relation of skin conductance response to dopaminergic neurotransmission and sensation-seeking. / Peterson, Ericka; Møller, Arne; Doudet, Doris J.; Bailey, Christopher J.; Hansen, Kim Vang; Rodell, Anders; Linnet, Jakob; Gjedde, Albert.

In: European Neuropsychopharmacology, Vol. 20, No. 11, 11.2010, p. 766-775.

Research output: Contribution to journalArticle

Peterson, E, Møller, A, Doudet, DJ, Bailey, CJ, Hansen, KV, Rodell, A, Linnet, J & Gjedde, A 2010, 'Pathological gambling: Relation of skin conductance response to dopaminergic neurotransmission and sensation-seeking', European Neuropsychopharmacology, vol. 20, no. 11, pp. 766-775. https://doi.org/10.1016/j.euroneuro.2010.07.010
Peterson, Ericka ; Møller, Arne ; Doudet, Doris J. ; Bailey, Christopher J. ; Hansen, Kim Vang ; Rodell, Anders ; Linnet, Jakob ; Gjedde, Albert. / Pathological gambling : Relation of skin conductance response to dopaminergic neurotransmission and sensation-seeking. In: European Neuropsychopharmacology. 2010 ; Vol. 20, No. 11. pp. 766-775.
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