Pathological analysis of myocardial cell under ventricular tachycardia and fibrillation based on symbolic dynamics

Z. Hongxuan, Z. Yisheng, X. Yuhong, N. V. Thakor

Research output: Contribution to journalArticlepeer-review

Abstract

Ventricular fibrillation (VF) is one of the most serious malignant arrhythmias usually resulting from immediate degeneration of ventricular tachycardia (VT). In order to analyse the nonlinear dynamics of the cardiac micro-mechanism under VT and VF rhythm, at the cellular level, myocardial cell action potentials are investigated under different rhythm, normal sinus rhythm, VT and VF. On the basis of nonlinear chaotic theory and symbolic dynamics, we put forward new definitions, complexity rate, etc, and obtained some useful properties for cellular electrophysiological analysis. The results of the experiments and computation show that the myocardial cellular signals under VT and VF rhythm are different kinds of chaotic signals in that the cardiac chaos attractor under VF is higher than that under VT. The analytical complexity theory has been promising in the clinical application.

Original languageEnglish (US)
Pages (from-to)112-117
Number of pages6
JournalJournal of Medical Engineering and Technology
Volume25
Issue number3
DOIs
StatePublished - 2001
Externally publishedYes

ASJC Scopus subject areas

  • Biomedical Engineering

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