Pathogenetic factors of aging macular degeneration

Research output: Contribution to journalArticle

Abstract

In order to explore the pathogenetic factors of aging macular degeneration, risk factors from epidemiologic studies and causative factors from clinical and laboratory studies were reviewed. From the epidemiologic studies, the risk factors of senile macular degeneration included: (1) personal characteristics such as age, race, height, family history, and strength of hand grip; (2) ocular characteristics such as hyperopia, color of iris and senile cataract, and (3) systemic diseases and environmental exposure such as cardiovascular diseases, smoking, lung infections, and chemical exposures. The causative factors suggested from clinical and laboratory studies include: drusen, choroidal vascular diseases, photic injury, and vitamin C deficiency. It is postulated that aging macular degeneration is a multifactorial syndrome. Different etiologic factors may inflict damaging effect on the macula, resulting in a common set of clinical manifestations that are interpreted as aging macular degeneration.

Original languageEnglish (US)
Pages (from-to)628-635
Number of pages8
JournalOphthalmology
Volume92
Issue number5
StatePublished - 1985
Externally publishedYes

Fingerprint

Macular Degeneration
Hand Strength
Epidemiologic Studies
Choroid Diseases
Ascorbic Acid Deficiency
Hyperopia
Environmental Exposure
Iris
Vascular Diseases
Cataract
Cardiovascular Diseases
Color
Smoking
Lung
Wounds and Injuries
Infection
Clinical Studies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Pathogenetic factors of aging macular degeneration. / Tso, M. O M.

In: Ophthalmology, Vol. 92, No. 5, 1985, p. 628-635.

Research output: Contribution to journalArticle

@article{507639c146b8466ca4d9e8f45fd7ad43,
title = "Pathogenetic factors of aging macular degeneration",
abstract = "In order to explore the pathogenetic factors of aging macular degeneration, risk factors from epidemiologic studies and causative factors from clinical and laboratory studies were reviewed. From the epidemiologic studies, the risk factors of senile macular degeneration included: (1) personal characteristics such as age, race, height, family history, and strength of hand grip; (2) ocular characteristics such as hyperopia, color of iris and senile cataract, and (3) systemic diseases and environmental exposure such as cardiovascular diseases, smoking, lung infections, and chemical exposures. The causative factors suggested from clinical and laboratory studies include: drusen, choroidal vascular diseases, photic injury, and vitamin C deficiency. It is postulated that aging macular degeneration is a multifactorial syndrome. Different etiologic factors may inflict damaging effect on the macula, resulting in a common set of clinical manifestations that are interpreted as aging macular degeneration.",
author = "Tso, {M. O M}",
year = "1985",
language = "English (US)",
volume = "92",
pages = "628--635",
journal = "Ophthalmology",
issn = "0161-6420",
publisher = "Elsevier Inc.",
number = "5",

}

TY - JOUR

T1 - Pathogenetic factors of aging macular degeneration

AU - Tso, M. O M

PY - 1985

Y1 - 1985

N2 - In order to explore the pathogenetic factors of aging macular degeneration, risk factors from epidemiologic studies and causative factors from clinical and laboratory studies were reviewed. From the epidemiologic studies, the risk factors of senile macular degeneration included: (1) personal characteristics such as age, race, height, family history, and strength of hand grip; (2) ocular characteristics such as hyperopia, color of iris and senile cataract, and (3) systemic diseases and environmental exposure such as cardiovascular diseases, smoking, lung infections, and chemical exposures. The causative factors suggested from clinical and laboratory studies include: drusen, choroidal vascular diseases, photic injury, and vitamin C deficiency. It is postulated that aging macular degeneration is a multifactorial syndrome. Different etiologic factors may inflict damaging effect on the macula, resulting in a common set of clinical manifestations that are interpreted as aging macular degeneration.

AB - In order to explore the pathogenetic factors of aging macular degeneration, risk factors from epidemiologic studies and causative factors from clinical and laboratory studies were reviewed. From the epidemiologic studies, the risk factors of senile macular degeneration included: (1) personal characteristics such as age, race, height, family history, and strength of hand grip; (2) ocular characteristics such as hyperopia, color of iris and senile cataract, and (3) systemic diseases and environmental exposure such as cardiovascular diseases, smoking, lung infections, and chemical exposures. The causative factors suggested from clinical and laboratory studies include: drusen, choroidal vascular diseases, photic injury, and vitamin C deficiency. It is postulated that aging macular degeneration is a multifactorial syndrome. Different etiologic factors may inflict damaging effect on the macula, resulting in a common set of clinical manifestations that are interpreted as aging macular degeneration.

UR - http://www.scopus.com/inward/record.url?scp=0021846717&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0021846717&partnerID=8YFLogxK

M3 - Article

C2 - 2409505

AN - SCOPUS:0021846717

VL - 92

SP - 628

EP - 635

JO - Ophthalmology

JF - Ophthalmology

SN - 0161-6420

IS - 5

ER -