Pathogenesis of oxalate urolithiasis: Lessons from experimental studies with rats

S. R. Khan

Research output: Contribution to journalArticle

Abstract

Calcium oxalate (CaOx) urolithiasis in rats is induced by producing hyperoxaluria. Depending on the degree and length of hyperoxaluria, CaOx crystals may either form in the nephron or the bladder and may or may not be retained in the kidneys. Crystals may nucleate in one part of the nephron and be retained in another part. Papillary collecting duct tubular epithelium and its basement membrane appear to be involved in crystal retention in the kidneys.

Original languageEnglish (US)
Pages (from-to)398-401
Number of pages4
JournalAmerican Journal of Kidney Diseases
Volume17
Issue number4
StatePublished - 1991
Externally publishedYes

Fingerprint

Hyperoxaluria
Urolithiasis
Oxalates
Nephrons
Kidney
Calcium Oxalate
Basement Membrane
Urinary Bladder
Epithelium
Calcium Oxalate Nephrolithiasis

ASJC Scopus subject areas

  • Nephrology

Cite this

Pathogenesis of oxalate urolithiasis : Lessons from experimental studies with rats. / Khan, S. R.

In: American Journal of Kidney Diseases, Vol. 17, No. 4, 1991, p. 398-401.

Research output: Contribution to journalArticle

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