Abstract
Over the past decade, there has been a significant increase in the number of patients with a variety of malignant and nonmalignant disorders referred for bone marrow transplantation. Despite numerous advances in the care of such patients after allogeneic bone marrow transplantation, acute and chronic graft-vs.-host disease continues to be a prinicipal cause of morbidity and mortality. In this article, we will present an overview of the pathogenesis, clinical presentation, and pathological manifestations of these two major complications.
Original language | English (US) |
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Pages (from-to) | 196-212 |
Number of pages | 17 |
Journal | American Journal of Pediatric Hematology/Oncology |
Volume | 11 |
Issue number | 2 |
State | Published - Jan 1 1989 |
Keywords
- Bone marrow transplantation
- Graft-vs.-host disease
- Pathogenesis
- Pathology
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Hematology
- Oncology