Patches and fences: Probing for plasma membrane domains

Research output: Contribution to journalArticlepeer-review

Abstract

Cell plasma membranes appear to be composed of domains, patches whose composition and function differ from the average for an entire membrane surface. Proteins and lipids may be segregated into domains by different mechanisms. Some of these mechanisms are discussed, followed by a summary of the evidence for membrane domains obtained in my laboratory. This evidence is largely based on measurements of the lateral diffusion of membrane proteins and lipids. Recent new approaches to the interpretation of lateral diffusion measurements, consideration of so-called fractal or long time-tails promise to give new insights into the stability and lifetime of membrane domains.

Original languageEnglish (US)
Pages (from-to)165-169
Number of pages5
JournalJournal of cell science
Volume106
Issue numberSUPPL. 17
DOIs
StatePublished - 1993

Keywords

  • Domains
  • FPR
  • Fluorescence
  • Lateral diffusion
  • Plasma membrane

ASJC Scopus subject areas

  • Cell Biology

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