Particulate air pollution and susceptibility to the development of pulmonary tuberculosis disease in North Carolina: An ecological study

Genee S. Smith, Victor J. Schoenbach, David B. Richardson, Marilie D. Gammon

Research output: Contribution to journalArticlepeer-review

Abstract

Although Mycobacterium tuberculosis is the causative agent of pulmonary tuberculosis (PTB), environmental factors may influence disease progression. Ecologic studies conducted in countries outside the USA with high levels of air pollution and PTB have suggested a link between active disease and ambient air pollution. The present investigation is the first to examine the ambient air pollution-PTB association in a country, where air pollution levels are comparatively lower. We used Poisson regression models to examine the association of outdoor air pollutants, PM10 and PM2.5 with rates of PTB in North Carolina residents during 1993-2007. Results suggest a potential association between long-term exposure to particulate matter (PM) and PTB disease. In view of the high levels of air pollution and high rates of PTB worldwide, a potential association between ambient air pollution and tuberculosis warrants further study.

Original languageEnglish (US)
Pages (from-to)103-112
Number of pages10
JournalInternational Journal of Environmental Health Research
Volume24
Issue number2
DOIs
StatePublished - Mar 4 2014
Externally publishedYes

Keywords

  • Pulmonary tuberculosis
  • air pollution
  • epidemiology
  • particulate matter

ASJC Scopus subject areas

  • Pollution
  • Public Health, Environmental and Occupational Health
  • Health, Toxicology and Mutagenesis

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