Partial nephrectomy for the treatment of translocation renal cell carcinoma

Research output: Contribution to journalArticle

Abstract

Abstract Background The aim of this study was to evaluate the outcome of patients with translocation renal cell carcinoma (RCC) treated with partial nephrectomy. Patients and Methods Our institutional review board-approved renal mass registry was queried for patients who underwent partial nephrectomy for a pathologically confirmed translocation RCC. We describe the demographic, clinical, pathological, and follow-up data for this series of patients. Results Between 2003 and 2013, 1897 patients with RCC were treated at our institution with a radical or partial nephrectomy. In total, 10 (0.5%) patients were diagnosed with a translocation RCC. Of these patients, 4 (40%) underwent treatment with partial nephrectomy for an incidentally detected small renal mass (mean imaging diameter, 2.6 cm [range, 1.0-4.2 cm]). During a mean follow-up of 37 months (range, 8-81 months), all patients were alive without evidence of disease. Conclusion At short-term follow-up, partial nephrectomy appears to be an effective treatment option for patients with small translocation RCCs. Larger studies are required to more extensively investigate the optimal treatment of these potentially aggressive tumors.

Original languageEnglish (US)
Article number353
Pages (from-to)e199-e201
JournalClinical Genitourinary Cancer
Volume13
Issue number3
DOIs
StatePublished - Jun 1 2015

Fingerprint

Nephrectomy
Renal Cell Carcinoma
Therapeutics
Kidney
Research Ethics Committees
Registries
Demography

Keywords

  • TFE3
  • TFEB
  • Xp11.2

ASJC Scopus subject areas

  • Oncology
  • Urology

Cite this

Partial nephrectomy for the treatment of translocation renal cell carcinoma. / Gorin, Michael; Ball, Mark W.; Pierorazio, Phillip Martin; Argani, Pedram; Allaf, Mohamad E.

In: Clinical Genitourinary Cancer, Vol. 13, No. 3, 353, 01.06.2015, p. e199-e201.

Research output: Contribution to journalArticle

@article{69190e8d57cc4f6ea21c97e789984a6d,
title = "Partial nephrectomy for the treatment of translocation renal cell carcinoma",
abstract = "Abstract Background The aim of this study was to evaluate the outcome of patients with translocation renal cell carcinoma (RCC) treated with partial nephrectomy. Patients and Methods Our institutional review board-approved renal mass registry was queried for patients who underwent partial nephrectomy for a pathologically confirmed translocation RCC. We describe the demographic, clinical, pathological, and follow-up data for this series of patients. Results Between 2003 and 2013, 1897 patients with RCC were treated at our institution with a radical or partial nephrectomy. In total, 10 (0.5{\%}) patients were diagnosed with a translocation RCC. Of these patients, 4 (40{\%}) underwent treatment with partial nephrectomy for an incidentally detected small renal mass (mean imaging diameter, 2.6 cm [range, 1.0-4.2 cm]). During a mean follow-up of 37 months (range, 8-81 months), all patients were alive without evidence of disease. Conclusion At short-term follow-up, partial nephrectomy appears to be an effective treatment option for patients with small translocation RCCs. Larger studies are required to more extensively investigate the optimal treatment of these potentially aggressive tumors.",
keywords = "TFE3, TFEB, Xp11.2",
author = "Michael Gorin and Ball, {Mark W.} and Pierorazio, {Phillip Martin} and Pedram Argani and Allaf, {Mohamad E}",
year = "2015",
month = "6",
day = "1",
doi = "10.1016/j.clgc.2014.12.008",
language = "English (US)",
volume = "13",
pages = "e199--e201",
journal = "Clinical Genitourinary Cancer",
issn = "1558-7673",
publisher = "Elsevier",
number = "3",

}

TY - JOUR

T1 - Partial nephrectomy for the treatment of translocation renal cell carcinoma

AU - Gorin, Michael

AU - Ball, Mark W.

AU - Pierorazio, Phillip Martin

AU - Argani, Pedram

AU - Allaf, Mohamad E

PY - 2015/6/1

Y1 - 2015/6/1

N2 - Abstract Background The aim of this study was to evaluate the outcome of patients with translocation renal cell carcinoma (RCC) treated with partial nephrectomy. Patients and Methods Our institutional review board-approved renal mass registry was queried for patients who underwent partial nephrectomy for a pathologically confirmed translocation RCC. We describe the demographic, clinical, pathological, and follow-up data for this series of patients. Results Between 2003 and 2013, 1897 patients with RCC were treated at our institution with a radical or partial nephrectomy. In total, 10 (0.5%) patients were diagnosed with a translocation RCC. Of these patients, 4 (40%) underwent treatment with partial nephrectomy for an incidentally detected small renal mass (mean imaging diameter, 2.6 cm [range, 1.0-4.2 cm]). During a mean follow-up of 37 months (range, 8-81 months), all patients were alive without evidence of disease. Conclusion At short-term follow-up, partial nephrectomy appears to be an effective treatment option for patients with small translocation RCCs. Larger studies are required to more extensively investigate the optimal treatment of these potentially aggressive tumors.

AB - Abstract Background The aim of this study was to evaluate the outcome of patients with translocation renal cell carcinoma (RCC) treated with partial nephrectomy. Patients and Methods Our institutional review board-approved renal mass registry was queried for patients who underwent partial nephrectomy for a pathologically confirmed translocation RCC. We describe the demographic, clinical, pathological, and follow-up data for this series of patients. Results Between 2003 and 2013, 1897 patients with RCC were treated at our institution with a radical or partial nephrectomy. In total, 10 (0.5%) patients were diagnosed with a translocation RCC. Of these patients, 4 (40%) underwent treatment with partial nephrectomy for an incidentally detected small renal mass (mean imaging diameter, 2.6 cm [range, 1.0-4.2 cm]). During a mean follow-up of 37 months (range, 8-81 months), all patients were alive without evidence of disease. Conclusion At short-term follow-up, partial nephrectomy appears to be an effective treatment option for patients with small translocation RCCs. Larger studies are required to more extensively investigate the optimal treatment of these potentially aggressive tumors.

KW - TFE3

KW - TFEB

KW - Xp11.2

UR - http://www.scopus.com/inward/record.url?scp=84929131312&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84929131312&partnerID=8YFLogxK

U2 - 10.1016/j.clgc.2014.12.008

DO - 10.1016/j.clgc.2014.12.008

M3 - Article

VL - 13

SP - e199-e201

JO - Clinical Genitourinary Cancer

JF - Clinical Genitourinary Cancer

SN - 1558-7673

IS - 3

M1 - 353

ER -