Part II. The prognostic significance of stromal eosinophilia in head and neck cancer

Manning M. Goldsmith; David H. Cresson; Frederic B. Askin

doi:10.1177/019459988709600403

Part II. The prognostic significance of stromal eosinophilia in head and neck cancer

Manning M. Goldsmith, David H. Cresson, Frederic B. Askin

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41 Scopus citations

Abstract

The pathologies of 82 head and neck tumors were examined for histologic features suggestive of poor prognoses. Twelve descriptive histopathologic variables, including two grading scales for malignant tumors, were correlated with DNA flow cytometric data and clinical outcome. We found no correlation between the grading scales and DNA flow cytometric data or clinical outcome. Only one of the histopathologic variables—stromal eosinophilia—was found to significantly correlate with favorable outcome (p = .018). Stromal eosinophilia may be an important new prognostic indicator for head and neck cancer.

Original language	English (US)
Pages (from-to)	319-324
Number of pages	6
Journal	Otolaryngology-Head and Neck Surgery
Volume	96
Issue number	4
DOIs	https://doi.org/10.1177/019459988709600403
State	Published - Apr 1987
Externally published	Yes

ASJC Scopus subject areas

Surgery
Otorhinolaryngology

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abstract = "The pathologies of 82 head and neck tumors were examined for histologic features suggestive of poor prognoses. Twelve descriptive histopathologic variables, including two grading scales for malignant tumors, were correlated with DNA flow cytometric data and clinical outcome. We found no correlation between the grading scales and DNA flow cytometric data or clinical outcome. Only one of the histopathologic variables—stromal eosinophilia—was found to significantly correlate with favorable outcome (p = .018). Stromal eosinophilia may be an important new prognostic indicator for head and neck cancer.",

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AU - Cresson, David H.

AU - Askin, Frederic B.

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N2 - The pathologies of 82 head and neck tumors were examined for histologic features suggestive of poor prognoses. Twelve descriptive histopathologic variables, including two grading scales for malignant tumors, were correlated with DNA flow cytometric data and clinical outcome. We found no correlation between the grading scales and DNA flow cytometric data or clinical outcome. Only one of the histopathologic variables—stromal eosinophilia—was found to significantly correlate with favorable outcome (p = .018). Stromal eosinophilia may be an important new prognostic indicator for head and neck cancer.

AB - The pathologies of 82 head and neck tumors were examined for histologic features suggestive of poor prognoses. Twelve descriptive histopathologic variables, including two grading scales for malignant tumors, were correlated with DNA flow cytometric data and clinical outcome. We found no correlation between the grading scales and DNA flow cytometric data or clinical outcome. Only one of the histopathologic variables—stromal eosinophilia—was found to significantly correlate with favorable outcome (p = .018). Stromal eosinophilia may be an important new prognostic indicator for head and neck cancer.

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Part II. The prognostic significance of stromal eosinophilia in head and neck cancer

Abstract

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