Abstract
Neurotensin receptor autoradiography reveals dense binding in normal human substantia nigra. In nigra from patients with Parkinson's disease, nigral receptor binding is only about one-third of control values. 'Saturation' analysis suggests that these changes result from receptor loss. These results support a neurotensin-domapine interaction in human nigro-striatal circuits.
Original language | English (US) |
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Pages (from-to) | 186-190 |
Number of pages | 5 |
Journal | Brain research |
Volume | 308 |
Issue number | 1 |
DOIs | |
State | Published - Aug 6 1984 |
Keywords
- Parkinson's disease
- neurotensin
- peptide
- receptor autoradiography
- substantia nigra
ASJC Scopus subject areas
- General Neuroscience
- Molecular Biology
- Clinical Neurology
- Developmental Biology