TY - JOUR
T1 - Parental body mass index and blood pressure are associated with higher body mass index and blood pressure in their adult offspring
T2 - a cross-sectional study in a resource-limited setting in northern Peru
AU - Carrillo-Larco, Rodrigo M.
AU - Bernabé-Ortiz, Antonio
AU - Sal y Rosas, Víctor G.
AU - Sacksteder, Katherine A.
AU - Diez-Canseco, Francisco
AU - Cárdenas, María K.
AU - Gilman, Robert H.
AU - Miranda, J. Jaime
N1 - Funding Information:
The authors are indebted to all the participants who kindly agreed to collaborate in the study. Special thanks to all field teams for their commitment and hard work. This study was supported by the National Heart, Lung, and Blood Institute (Project 1 U01 HL114180-01), United States, under The Global Alliance for Chronic Diseases (GACD) programme. CRONICAS Center of Excellence in Chronic Diseases is supported by the National Heart, Lung, and Blood Institute Global Health Initiative under the contract Global Health Activities in Developing Countries to Combat Non-Communicable Chronic Diseases (Project Number 268200900033C-1-0-1). RMC-L has received support as a research trainee from the Inter-American Institute for Global Change Research (IAI CRN3036). AB-O is a Wellcome Trust Research Training Fellow in Public Health and Tropical Medicine (103994/Z/14/Z). VGSyR was funded by the Dirección de Gestión de la Investigación at the PUCP through grant DGI-2015-200.
Publisher Copyright:
© 2018 The Authors. Tropical Medicine & International Health Published by John Wiley & Sons Ltd.
PY - 2018/5
Y1 - 2018/5
N2 - Objectives: High body mass index (BMI) and blood pressure (BP) are major contributors to the high burden of non-communicable diseases in adulthood. Individual high-risk and population approaches for prevention require newer strategies to target these risk factors and focusing on the family to introduce prevention initiatives appears as a promising scenario. Characterisation of the relationship between BMI and BP among the adult members of a given family merits evaluation. We conducted a secondary analysis of an implementation study in Tumbes, Peru, benefiting from data derived from families with at least one adult offspring. Methods: The exposures of interest were the BMI, systolic BP (SBP) and diastolic BP (DBP) of the mother and father. The outcomes were the BMI, SBP and DBP of the offspring. Mixed-effects linear regression models were conducted. Results: The mean age of the offspring, mothers and fathers was 29 (SD: 9.5), 54 (SD: 11.8) and 59 (SD: 11.6) years, respectively. Father's BMI was associated with a quarter-point increase in offspring BMI, regardless of the sex of the offspring. Mother's BMI had a similar effect on the BMI of her sons, but had no significant effect on her daughters’. Mother's SBP was associated with almost one-tenth of mmHg increase in the SBP of the adult offspring. There was no evidence of an association for DBP. Conclusions: In families with adult members, the higher the parents’ BMI and SBP, the higher their adult offspring's levels will be.
AB - Objectives: High body mass index (BMI) and blood pressure (BP) are major contributors to the high burden of non-communicable diseases in adulthood. Individual high-risk and population approaches for prevention require newer strategies to target these risk factors and focusing on the family to introduce prevention initiatives appears as a promising scenario. Characterisation of the relationship between BMI and BP among the adult members of a given family merits evaluation. We conducted a secondary analysis of an implementation study in Tumbes, Peru, benefiting from data derived from families with at least one adult offspring. Methods: The exposures of interest were the BMI, systolic BP (SBP) and diastolic BP (DBP) of the mother and father. The outcomes were the BMI, SBP and DBP of the offspring. Mixed-effects linear regression models were conducted. Results: The mean age of the offspring, mothers and fathers was 29 (SD: 9.5), 54 (SD: 11.8) and 59 (SD: 11.6) years, respectively. Father's BMI was associated with a quarter-point increase in offspring BMI, regardless of the sex of the offspring. Mother's BMI had a similar effect on the BMI of her sons, but had no significant effect on her daughters’. Mother's SBP was associated with almost one-tenth of mmHg increase in the SBP of the adult offspring. There was no evidence of an association for DBP. Conclusions: In families with adult members, the higher the parents’ BMI and SBP, the higher their adult offspring's levels will be.
KW - blood pressure
KW - body mass index
KW - family health
KW - hypertension
KW - obesity
KW - overweight
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U2 - 10.1111/tmi.13052
DO - 10.1111/tmi.13052
M3 - Article
C2 - 29575646
AN - SCOPUS:85044734902
SN - 1360-2276
VL - 23
SP - 533
EP - 540
JO - Tropical Medicine and International Health
JF - Tropical Medicine and International Health
IS - 5
ER -