Parenchymal abnormalities associated with developmental venous anomalies

Diego San Millán Ruíz, Jacqueline Delavelle, Hasan Yilmaz, Philippe Gailloud, Enrico Piovan, Alberto Bertramello, Francesca Pizzini, Daniel A. Rüfenacht

Research output: Contribution to journalArticle

Abstract

Introduction: To report a retrospective series of 84 cerebral developmental venous anomalies (DVAs), focusing on associated parenchymal abnormalities within the drainage territory of the DVA. Methods: DVAs were identified during routine diagnostic radiological work-up based on magnetic resonance imaging (MRI) (60 cases), computed tomography (CT) (62 cases) or both (36 cases). Regional parenchymal modifications within the drainage territory of the DVA, such as cortical or subcortical atrophy, white matter density or signal alterations, dystrophic calcifications, presence of haemorrhage or a cavernous-like vascular malformation (CVM), were noted. A stenosis of the collecting vein of the DVA was also sought for. Results: Brain abnormalities within the drainage territory of a DVA were encountered in 65.4% of the cases. Locoregional brain atrophy occurred in 29.7% of the cases, followed by white matter lesions in 28.3% of MRI investigations and 19.3% of CT investigations, CVMs in 13.3% of MRI investigations and dystrophic calcification in 9.6% of CT investigations. An intracranial haemorrhage possibly related to a DVA occurred in 2.4% cases, and a stenosis on the collecting vein was documented in 13.1% of cases. Parenchymal abnormalities were identified for all DVA sizes. Conclusion: Brain parenchymal abnormalities were associated with DVAs in close to two thirds of the cases evaluated. These abnormalities are thought to occur secondarily, likely during post-natal life, as a result of chronic venous hypertension. Outflow obstruction, progressive thickening of the walls of the DVA and their morphological organization into a venous convergence zone are thought to contribute to the development of venous hypertension in DVA.

Original languageEnglish (US)
Pages (from-to)987-995
Number of pages9
JournalNeuroradiology
Volume49
Issue number12
DOIs
StatePublished - Dec 2007

Fingerprint

Drainage
Tomography
Magnetic Resonance Imaging
Atrophy
Veins
Pathologic Constriction
Brain
Hypertension
Vascular Malformations
Intracranial Hemorrhages
Hemorrhage
White Matter

Keywords

  • Developmental venous anomaly
  • Regional parenchymal brain abnormalities
  • Venous hypertension

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Clinical Neurology
  • Radiological and Ultrasound Technology

Cite this

San Millán Ruíz, D., Delavelle, J., Yilmaz, H., Gailloud, P., Piovan, E., Bertramello, A., ... Rüfenacht, D. A. (2007). Parenchymal abnormalities associated with developmental venous anomalies. Neuroradiology, 49(12), 987-995. https://doi.org/10.1007/s00234-007-0279-0

Parenchymal abnormalities associated with developmental venous anomalies. / San Millán Ruíz, Diego; Delavelle, Jacqueline; Yilmaz, Hasan; Gailloud, Philippe; Piovan, Enrico; Bertramello, Alberto; Pizzini, Francesca; Rüfenacht, Daniel A.

In: Neuroradiology, Vol. 49, No. 12, 12.2007, p. 987-995.

Research output: Contribution to journalArticle

San Millán Ruíz, D, Delavelle, J, Yilmaz, H, Gailloud, P, Piovan, E, Bertramello, A, Pizzini, F & Rüfenacht, DA 2007, 'Parenchymal abnormalities associated with developmental venous anomalies', Neuroradiology, vol. 49, no. 12, pp. 987-995. https://doi.org/10.1007/s00234-007-0279-0
San Millán Ruíz D, Delavelle J, Yilmaz H, Gailloud P, Piovan E, Bertramello A et al. Parenchymal abnormalities associated with developmental venous anomalies. Neuroradiology. 2007 Dec;49(12):987-995. https://doi.org/10.1007/s00234-007-0279-0
San Millán Ruíz, Diego ; Delavelle, Jacqueline ; Yilmaz, Hasan ; Gailloud, Philippe ; Piovan, Enrico ; Bertramello, Alberto ; Pizzini, Francesca ; Rüfenacht, Daniel A. / Parenchymal abnormalities associated with developmental venous anomalies. In: Neuroradiology. 2007 ; Vol. 49, No. 12. pp. 987-995.
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abstract = "Introduction: To report a retrospective series of 84 cerebral developmental venous anomalies (DVAs), focusing on associated parenchymal abnormalities within the drainage territory of the DVA. Methods: DVAs were identified during routine diagnostic radiological work-up based on magnetic resonance imaging (MRI) (60 cases), computed tomography (CT) (62 cases) or both (36 cases). Regional parenchymal modifications within the drainage territory of the DVA, such as cortical or subcortical atrophy, white matter density or signal alterations, dystrophic calcifications, presence of haemorrhage or a cavernous-like vascular malformation (CVM), were noted. A stenosis of the collecting vein of the DVA was also sought for. Results: Brain abnormalities within the drainage territory of a DVA were encountered in 65.4{\%} of the cases. Locoregional brain atrophy occurred in 29.7{\%} of the cases, followed by white matter lesions in 28.3{\%} of MRI investigations and 19.3{\%} of CT investigations, CVMs in 13.3{\%} of MRI investigations and dystrophic calcification in 9.6{\%} of CT investigations. An intracranial haemorrhage possibly related to a DVA occurred in 2.4{\%} cases, and a stenosis on the collecting vein was documented in 13.1{\%} of cases. Parenchymal abnormalities were identified for all DVA sizes. Conclusion: Brain parenchymal abnormalities were associated with DVAs in close to two thirds of the cases evaluated. These abnormalities are thought to occur secondarily, likely during post-natal life, as a result of chronic venous hypertension. Outflow obstruction, progressive thickening of the walls of the DVA and their morphological organization into a venous convergence zone are thought to contribute to the development of venous hypertension in DVA.",
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AU - Pizzini, Francesca

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N2 - Introduction: To report a retrospective series of 84 cerebral developmental venous anomalies (DVAs), focusing on associated parenchymal abnormalities within the drainage territory of the DVA. Methods: DVAs were identified during routine diagnostic radiological work-up based on magnetic resonance imaging (MRI) (60 cases), computed tomography (CT) (62 cases) or both (36 cases). Regional parenchymal modifications within the drainage territory of the DVA, such as cortical or subcortical atrophy, white matter density or signal alterations, dystrophic calcifications, presence of haemorrhage or a cavernous-like vascular malformation (CVM), were noted. A stenosis of the collecting vein of the DVA was also sought for. Results: Brain abnormalities within the drainage territory of a DVA were encountered in 65.4% of the cases. Locoregional brain atrophy occurred in 29.7% of the cases, followed by white matter lesions in 28.3% of MRI investigations and 19.3% of CT investigations, CVMs in 13.3% of MRI investigations and dystrophic calcification in 9.6% of CT investigations. An intracranial haemorrhage possibly related to a DVA occurred in 2.4% cases, and a stenosis on the collecting vein was documented in 13.1% of cases. Parenchymal abnormalities were identified for all DVA sizes. Conclusion: Brain parenchymal abnormalities were associated with DVAs in close to two thirds of the cases evaluated. These abnormalities are thought to occur secondarily, likely during post-natal life, as a result of chronic venous hypertension. Outflow obstruction, progressive thickening of the walls of the DVA and their morphological organization into a venous convergence zone are thought to contribute to the development of venous hypertension in DVA.

AB - Introduction: To report a retrospective series of 84 cerebral developmental venous anomalies (DVAs), focusing on associated parenchymal abnormalities within the drainage territory of the DVA. Methods: DVAs were identified during routine diagnostic radiological work-up based on magnetic resonance imaging (MRI) (60 cases), computed tomography (CT) (62 cases) or both (36 cases). Regional parenchymal modifications within the drainage territory of the DVA, such as cortical or subcortical atrophy, white matter density or signal alterations, dystrophic calcifications, presence of haemorrhage or a cavernous-like vascular malformation (CVM), were noted. A stenosis of the collecting vein of the DVA was also sought for. Results: Brain abnormalities within the drainage territory of a DVA were encountered in 65.4% of the cases. Locoregional brain atrophy occurred in 29.7% of the cases, followed by white matter lesions in 28.3% of MRI investigations and 19.3% of CT investigations, CVMs in 13.3% of MRI investigations and dystrophic calcification in 9.6% of CT investigations. An intracranial haemorrhage possibly related to a DVA occurred in 2.4% cases, and a stenosis on the collecting vein was documented in 13.1% of cases. Parenchymal abnormalities were identified for all DVA sizes. Conclusion: Brain parenchymal abnormalities were associated with DVAs in close to two thirds of the cases evaluated. These abnormalities are thought to occur secondarily, likely during post-natal life, as a result of chronic venous hypertension. Outflow obstruction, progressive thickening of the walls of the DVA and their morphological organization into a venous convergence zone are thought to contribute to the development of venous hypertension in DVA.

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