Paraneoplastic bullous stomatitis in a horse.

M. A. Williams, P. M. Dowling, D. W. Angarano, A. A. Yu, B. J. DiFranco, S. D. Lenz, G. J. Anhalt

Research output: Contribution to journalArticlepeer-review

Abstract

An adult horse with a 2-month history of anorexia, ataxia, and oral blisters had developed these clinical signs just prior to the appearance and growth of a cervical mass. Bullous stomatitis was characterized histologically as subepidermal clefting. Clinical signs were unresponsive to treatment with antibiotics or corticosteroids; however, surgical removal of the mass coincided with remission of all signs. Histologic findings of the mass were consistent with hemangiosarcoma. Results of indirect immunofluorescence and immunoprecipitation on frozen serum from the horse were characteristic of paraneoplastic pemphigus in human beings, a newly recognized mucocutaneous autoimmune disease associated with neoplasia.

Original languageEnglish (US)
Pages (from-to)331-334
Number of pages4
JournalJournal of the American Veterinary Medical Association
Volume207
Issue number3
StatePublished - Aug 1 1995
Externally publishedYes

ASJC Scopus subject areas

  • veterinary(all)

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