Paramyxoviruses: Measles

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Measles is a highly contagious viral disease that is characterized by a prodromal illness of fever, cough, coryza, and conjunctivitis followed by the appearance of a generalized maculopapular rash. Before the widespread use of measles vaccines, it was estimated that measles caused between 5 million and 8 million deaths worldwide each year. Remarkable progress has been made in reducing global measles incidence and mortality rates through measles vaccination. Progress in global measles control has renewed discussion of measles eradication. In contrast to poliovirus eradication, the eradication of measles virus will not entail challenges posed by prolonged shedding of potentially virulent vaccine viruses and environmental viral reservoirs. However, higher levels of population immunity will be necessary to interrupt measles virus transmission, more highly skilled health care workers will be required to administer measles vaccines, and containment through case detection and ring vaccination will be more difficult for measles virus because of infectivity before rash onset. Despite enormous progress, measles remains a leading vaccine-preventable cause of childhood mortality worldwide and continues to cause outbreaks in communities with low vaccination.

Original languageEnglish (US)
Title of host publicationViral Infections of Humans
Subtitle of host publicationEpidemiology and Control
PublisherSpringer US
Pages537-552
Number of pages16
ISBN (Electronic)9781489974488
ISBN (Print)1489974474, 9781489974471
DOIs
StatePublished - Jun 1 2014

ASJC Scopus subject areas

  • Medicine(all)

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