Parameters of 99mTc-DTPA transfer function in renal artery stenosis

Z. Szabó, H. Vosberg, G. Torsello, W. Sandmann, L. E. Feinendegen

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A new method is presented for decomposition of 99mTc-DTPA renal transfer functions (TF) into their capillary and tubular parts. Amplitudes and mean transit times of both parts were calculated and used for quantitative evaluation of renal perfusion, extraction and transport in 21 patients with renal artery stenosis. The amplitudes showed a positive correlation to the effective renal plasma flow and a negative correlation to the grade of stenosis. The parameters of TF are independent of the contralateral kidney, so they can be used for screening for renovascular disease as well as for pre- and postoperative evaluation of kidneys even in cases of bilateral disease.

Original languageEnglish (US)
Pages (from-to)46-48
Number of pages3
JournalCardiology (Switzerland)
StatePublished - 1985
Externally publishedYes


  • Deconvolution analysis
  • Kidney
  • Renal artery stenosis
  • Technetium-99m-diethylenetriaminepentaacetic acid
  • Transfer function

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)


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