Parameters of 99mTc-DTPA transfer function in renal artery stenosis

Z. Szabó; H. Vosberg; G. Torsello; W. Sandmann; L. E. Feinendegen

doi:10.1159/000173943

Parameters of ^99mTc-DTPA transfer function in renal artery stenosis

Z. Szabó, H. Vosberg, G. Torsello, W. Sandmann, L. E. Feinendegen

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

A new method is presented for decomposition of ^99mTc-DTPA renal transfer functions (TF) into their capillary and tubular parts. Amplitudes and mean transit times of both parts were calculated and used for quantitative evaluation of renal perfusion, extraction and transport in 21 patients with renal artery stenosis. The amplitudes showed a positive correlation to the effective renal plasma flow and a negative correlation to the grade of stenosis. The parameters of TF are independent of the contralateral kidney, so they can be used for screening for renovascular disease as well as for pre- and postoperative evaluation of kidneys even in cases of bilateral disease.

Original language	English (US)
Pages (from-to)	46-48
Number of pages	3
Journal	Cardiology (Switzerland)
Volume	72
DOIs	https://doi.org/10.1159/000173943
State	Published - 1985
Externally published	Yes

Keywords

Deconvolution analysis
Kidney
Renal artery stenosis
Technetium-99m-diethylenetriaminepentaacetic acid
Transfer function

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Pharmacology (medical)

Access to Document

10.1159/000173943

Cite this

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title = "Parameters of 99mTc-DTPA transfer function in renal artery stenosis",

abstract = "A new method is presented for decomposition of 99mTc-DTPA renal transfer functions (TF) into their capillary and tubular parts. Amplitudes and mean transit times of both parts were calculated and used for quantitative evaluation of renal perfusion, extraction and transport in 21 patients with renal artery stenosis. The amplitudes showed a positive correlation to the effective renal plasma flow and a negative correlation to the grade of stenosis. The parameters of TF are independent of the contralateral kidney, so they can be used for screening for renovascular disease as well as for pre- and postoperative evaluation of kidneys even in cases of bilateral disease.",

keywords = "Deconvolution analysis, Kidney, Renal artery stenosis, Technetium-99m-diethylenetriaminepentaacetic acid, Transfer function",

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year = "1985",

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T1 - Parameters of 99mTc-DTPA transfer function in renal artery stenosis

AU - Szabó, Z.

AU - Vosberg, H.

AU - Torsello, G.

AU - Sandmann, W.

AU - Feinendegen, L. E.

PY - 1985

Y1 - 1985

N2 - A new method is presented for decomposition of 99mTc-DTPA renal transfer functions (TF) into their capillary and tubular parts. Amplitudes and mean transit times of both parts were calculated and used for quantitative evaluation of renal perfusion, extraction and transport in 21 patients with renal artery stenosis. The amplitudes showed a positive correlation to the effective renal plasma flow and a negative correlation to the grade of stenosis. The parameters of TF are independent of the contralateral kidney, so they can be used for screening for renovascular disease as well as for pre- and postoperative evaluation of kidneys even in cases of bilateral disease.

AB - A new method is presented for decomposition of 99mTc-DTPA renal transfer functions (TF) into their capillary and tubular parts. Amplitudes and mean transit times of both parts were calculated and used for quantitative evaluation of renal perfusion, extraction and transport in 21 patients with renal artery stenosis. The amplitudes showed a positive correlation to the effective renal plasma flow and a negative correlation to the grade of stenosis. The parameters of TF are independent of the contralateral kidney, so they can be used for screening for renovascular disease as well as for pre- and postoperative evaluation of kidneys even in cases of bilateral disease.

KW - Deconvolution analysis

KW - Kidney

KW - Renal artery stenosis

KW - Technetium-99m-diethylenetriaminepentaacetic acid

KW - Transfer function

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