Paperfluidic platform to detect neisseria gonorrhoeae in urethral and vaginal swab samples

A. L. Horst, J. M. Rosenbohm, N. Kolluri, Charlotte A Gaydos, J. Hardick, M. Cabodi, J. C. Linnes, C. M. Klapperich

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Globally, Neisseria gonorrhoeae (NG) accounts for 106 million new sexually transmitted infections (STIs) per year. Once diagnosed, this infection can be cured with a one-time dose of antimicrobial drug; however, gold standard NG diagnostics are often unavailable in resource-constrained settings and at the point-of-care, often resulting in patients remaining untreated. We have developed an integrated 'sample-to-answer' system that results in simple and sensitive Yes/No visual readout for NG on a paper microfluidic in less than an hour. Here, we show preliminary results using our diagnostic platform with banked NG clinical samples, showing agreement with gold standard PCR assay.

Original languageEnglish (US)
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
PublisherChemical and Biological Microsystems Society
Pages186-187
Number of pages2
ISBN (Electronic)9780979806490
StatePublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 - Dublin, Ireland
Duration: Oct 9 2016Oct 13 2016

Other

Other20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
CountryIreland
CityDublin
Period10/9/1610/13/16

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Keywords

  • Clinical sample
  • Diagnostics
  • Gonorrhea
  • Paperfluidics
  • Point-of-care

ASJC Scopus subject areas

  • Control and Systems Engineering

Cite this

Horst, A. L., Rosenbohm, J. M., Kolluri, N., Gaydos, C. A., Hardick, J., Cabodi, M., Linnes, J. C., & Klapperich, C. M. (2016). Paperfluidic platform to detect neisseria gonorrhoeae in urethral and vaginal swab samples. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 186-187). Chemical and Biological Microsystems Society.