Pancreatic Wounds Sealed With Plastic Adhesive: An Experimental Study in the Cat

John L Cameron, Stephen C. Woodward, John B. Herrmann

Research output: Contribution to journalArticle


Methyl-2-cyanoacrylate monomer is an effective pancreatic sealing agent in the cat.This material was applied to the resectedpancreatic surfaces of 15 cats following pancreatic duct ligation and segmental resectionof the pancreas. In 15 control cats identicallyprepared, but without monomer application,observation at 1, 7, and 30 days revealed thepreparations to be associated with the formation of fistulas, pseudocysts, peripancreaticfat necrosis, and diffuse fibrous adhesions.In the 15 methyl-2-cyanoacrylate-treatedanimals, pancreatic juice leakage was effectively prevented, since these sequelae wereabsent, even though the plastic was locallyhistotoxic.

Original languageEnglish (US)
Pages (from-to)546-553
Number of pages8
JournalArchives of Surgery
Issue number3
Publication statusPublished - 1964
Externally publishedYes


ASJC Scopus subject areas

  • Surgery

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