Pancreatic islet allograft prolongation by donor-specific blood transfusions treated with ultraviolet irradiation

Henry Lau, Keith Reemtsma, Mark A. Hardy

Research output: Contribution to journalArticlepeer-review

73 Scopus citations

Abstract

Survival of allografts of islets of Langerhans in nonimmunosuppressed adult rats was prolonged by transfusions of donor blood irradiated with ultraviolet light before transplantation across a major histocompatibility barrier. This treatment is donor blood-specific and has produced greater than 160-day survival of transplanted islets without the administration of immunosuppressive agents.

Original languageEnglish (US)
Pages (from-to)754-756
Number of pages3
JournalScience
Volume221
Issue number4612
StatePublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • General

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