Pancreatic insufficiency in patients with chronic graft-versus-host disease

G. Akpek, J. L. Valladares, L. Lee, J. Margolis, G. B. Vogelsang

Research output: Contribution to journalArticlepeer-review

Abstract

Diarrhea is a difficult diagnostic problem in patients with chronic graft-versus-host disease (cGVHD) because there are many causes of it. Although intestinal involvement has been reported in early studies of untreated cGVHD, this is now a very rare presentation of the disease. In addition to other etiologies, pancreatic insufficiency should also be considered in patients with cGVHD who demonstrate malabsorption. The pathogenesis of pancreatic insufficiency in these patients is unknown. Pancreatic enzyme supplements can be very effective in treating this rare condition.

Original languageEnglish (US)
Pages (from-to)163-166
Number of pages4
JournalBone marrow transplantation
Volume27
Issue number2
DOIs
StatePublished - 2001

Keywords

  • Chronic GVHD
  • Diarrhea
  • Malabsorption
  • Pancreas
  • Pancreatic insufficiency

ASJC Scopus subject areas

  • Hematology
  • Transplantation

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