Pancreatic cancer pathology viewed in the light of evolution

Research output: Contribution to journalReview articlepeer-review


One way to understand ductal adenocarcinoma of the pancreas (pancreatic cancer) is to view it as unimaginably large numbers of evolving living organisms interacting with their environment. This “evolutionary view” creates both expected and surprising perspectives in all stages of neoplastic progression. Advances in the field will require greater attention to this critical evolutionary prospective.

Original languageEnglish (US)
Pages (from-to)661-674
Number of pages14
JournalCancer and Metastasis Reviews
Issue number3
StatePublished - Sep 2021


  • Darwin
  • Evolution
  • Intraductal papillary mucinous neoplasm
  • Pancreas cancer
  • Pancreatic cancer
  • Pancreatic intraepithelial neoplasia

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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