Pancreatic cancer genomes: Toward molecular subtyping and novel approaches to diagnosis and therapy

Research output: Contribution to journalArticle

Abstract

Pancreatic neoplasms represent a broad range of clinical entities, many of which have drastic effects on the lives of patients. Recently, high-throughput sequencing analyses have been performed in many pancreatic neoplasms, providing deep insights into the underlying biology of these neoplasms as well as novel approaches to diagnosis and treatment. This review discusses the molecular alterations underlying pancreatic neoplasms as well as the clinical impact of these alterations for diagnosis and treatment.

Original languageEnglish (US)
Pages (from-to)287-297
Number of pages11
JournalMolecular Diagnosis and Therapy
Volume17
Issue number5
DOIs
StatePublished - Oct 2013

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Pancreatic Neoplasms
Genome
Therapeutics
Neoplasms

ASJC Scopus subject areas

  • Genetics
  • Molecular Medicine
  • Medicine(all)
  • Pharmacology

Cite this

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abstract = "Pancreatic neoplasms represent a broad range of clinical entities, many of which have drastic effects on the lives of patients. Recently, high-throughput sequencing analyses have been performed in many pancreatic neoplasms, providing deep insights into the underlying biology of these neoplasms as well as novel approaches to diagnosis and treatment. This review discusses the molecular alterations underlying pancreatic neoplasms as well as the clinical impact of these alterations for diagnosis and treatment.",
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