TY - JOUR
T1 - Pancreas transplantation
T2 - Contemporary surgical techniques
AU - Krishnamurthi, Venkatesh
AU - Philosophe, Benjamin
AU - Bartlett, Stephen T.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2001/11
Y1 - 2001/11
N2 - Since its inception more than 30 years ago, vascularized pancreas transplantation has undergone considerable progress. Given the unique complications associated with transplantation of this organ, modifications in surgical technique have been necessary to improve outcomes. As a result of these surgical advances and improvements in organ preservation and immunosuppression, contemporary graft survival rates approach 90% at 1 year. Despite this level of success, the technique of pancreas transplantation remains controversial. Future efforts to reduce morbidity and minimize immunosuppression will enable pancreas transplantation to remain an important therapeutic option for selected patients with type 1 diabetes mellitus.
AB - Since its inception more than 30 years ago, vascularized pancreas transplantation has undergone considerable progress. Given the unique complications associated with transplantation of this organ, modifications in surgical technique have been necessary to improve outcomes. As a result of these surgical advances and improvements in organ preservation and immunosuppression, contemporary graft survival rates approach 90% at 1 year. Despite this level of success, the technique of pancreas transplantation remains controversial. Future efforts to reduce morbidity and minimize immunosuppression will enable pancreas transplantation to remain an important therapeutic option for selected patients with type 1 diabetes mellitus.
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U2 - 10.1016/S0094-0143(01)80038-0
DO - 10.1016/S0094-0143(01)80038-0
M3 - Article
C2 - 11791499
AN - SCOPUS:0035660726
SN - 0094-0143
VL - 28
SP - 833
EP - 838
JO - Urologic Clinics of North America
JF - Urologic Clinics of North America
IS - 4
ER -