Palliative care and phase 1 trials

Intervention to improve quality of life and provide education

Betty Ferrell, Vincent Chung, Marianna Koczywas, Anna Cathy Williams, Denise Gallagher, Patricia Fischer, Thomas J Smith

Research output: Contribution to journalArticle

Abstract

Background: Patients in phase 1 clinical trials often have significant symptom burdens and quality-of-life concerns that increase as they progress along the cancer trajectory and experience drug toxicities from the clinical trial. Objectives: The interdisciplinary intervention described is aimed at providing optimum palliative care to support patients with solid tumors participating in a phase 1 clinical trial. Methods: The intervention includes a baseline evaluation using quantitative surveys, a comprehensive palliative care assessment by a research nurse based on patient baseline evaluation, and a goals-of-care discussion by the treating oncologist. The second component includes an interdisciplinary meeting where palliative care recommendations are made, followed by two patient education sessions. Findings: The initial experience with the palliative care intervention suggests a need for support for this population, as well as potential benefits from integrating palliative care for patients enrolled in phase 1 clinical trials.

Original languageEnglish (US)
Pages (from-to)473-479
Number of pages7
JournalClinical Journal of Oncology Nursing
Volume21
Issue number4
DOIs
StatePublished - 2017

Fingerprint

Palliative Care
Clinical Trials, Phase I
Quality of Life
Education
Patient Care Planning
Patient Education
Drug-Related Side Effects and Adverse Reactions
Neoplasms
Nurses
Clinical Trials
Research
Population

Keywords

  • Palliative care
  • Phase 1 clinical trials
  • Quality of life
  • Symptom burden

ASJC Scopus subject areas

  • Oncology
  • Oncology(nursing)

Cite this

Palliative care and phase 1 trials : Intervention to improve quality of life and provide education. / Ferrell, Betty; Chung, Vincent; Koczywas, Marianna; Williams, Anna Cathy; Gallagher, Denise; Fischer, Patricia; Smith, Thomas J.

In: Clinical Journal of Oncology Nursing, Vol. 21, No. 4, 2017, p. 473-479.

Research output: Contribution to journalArticle

Ferrell, Betty ; Chung, Vincent ; Koczywas, Marianna ; Williams, Anna Cathy ; Gallagher, Denise ; Fischer, Patricia ; Smith, Thomas J. / Palliative care and phase 1 trials : Intervention to improve quality of life and provide education. In: Clinical Journal of Oncology Nursing. 2017 ; Vol. 21, No. 4. pp. 473-479.
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