Palettes of vaccines and immunostimulatory monoclonal antibodies for combination

Ignacio Melero, Ivan Martinez-Forero, Juan Dubrot, Natalia Suarez, Asis Palazón, Lieping Chen

Research output: Contribution to journalArticle

Abstract

Various monoclonal antibodies (mAb) target immune system molecules to enhance immunity by costimulating T cells (i.e., CD137, OX40, CD40, GITR) or interfering in coinhibitory signals (i.e., CTLA-4, PD-1). These powerful agents can be guided by cancer vaccines to enhance immunity against tumor but not self tissues. Clinically powerful therapeutic synergies are at hand.

Original languageEnglish (US)
Pages (from-to)1507-1509
Number of pages3
JournalClinical Cancer Research
Volume15
Issue number5
DOIs
StatePublished - Mar 1 2009

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Immunity
Vaccines
Monoclonal Antibodies
Cancer Vaccines
Immune System
Hand
T-Lymphocytes
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

Cite this

Melero, I., Martinez-Forero, I., Dubrot, J., Suarez, N., Palazón, A., & Chen, L. (2009). Palettes of vaccines and immunostimulatory monoclonal antibodies for combination. Clinical Cancer Research, 15(5), 1507-1509. https://doi.org/10.1158/1078-0432.CCR-08-2931

Palettes of vaccines and immunostimulatory monoclonal antibodies for combination. / Melero, Ignacio; Martinez-Forero, Ivan; Dubrot, Juan; Suarez, Natalia; Palazón, Asis; Chen, Lieping.

In: Clinical Cancer Research, Vol. 15, No. 5, 01.03.2009, p. 1507-1509.

Research output: Contribution to journalArticle

Melero, I, Martinez-Forero, I, Dubrot, J, Suarez, N, Palazón, A & Chen, L 2009, 'Palettes of vaccines and immunostimulatory monoclonal antibodies for combination', Clinical Cancer Research, vol. 15, no. 5, pp. 1507-1509. https://doi.org/10.1158/1078-0432.CCR-08-2931
Melero I, Martinez-Forero I, Dubrot J, Suarez N, Palazón A, Chen L. Palettes of vaccines and immunostimulatory monoclonal antibodies for combination. Clinical Cancer Research. 2009 Mar 1;15(5):1507-1509. https://doi.org/10.1158/1078-0432.CCR-08-2931
Melero, Ignacio ; Martinez-Forero, Ivan ; Dubrot, Juan ; Suarez, Natalia ; Palazón, Asis ; Chen, Lieping. / Palettes of vaccines and immunostimulatory monoclonal antibodies for combination. In: Clinical Cancer Research. 2009 ; Vol. 15, No. 5. pp. 1507-1509.
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