Pain symptoms associated with opioid use among vulnerable persons with HIV: An exploratory study with implications for palliative care and opioid abuse prevention

Amy R. Knowlton, Trang O. Nguyen, Allysha C. Robinson, Paul T. Harrell, Mary M. Mitchell

Research output: Contribution to journalArticlepeer-review

Abstract

Current or former injection drug users with human immunodeficiency virus (H IV) are at high risk for pain, which adversely affects their quality of life and may increase their risk for illicit drug use or relapse. We explored associations between pain symptoms and substance use among injection-drug-using study participants with HIV who had histories of heroin use. Using generalized estimating equations and controlling for prior substance use, we found that pain in each six- month period was associated with the use of heroin and prescription opioids, but not the use of nonopioid drugs or alcohol. Routine clinical assessment and improved management of pain symptoms may be needed for persons with HIV and a history of injection drug use, particularly those with chronic pain, for whom there is increased risk for heroin use.

Original languageEnglish (US)
Pages (from-to)228-233
Number of pages6
JournalJournal of palliative care
Volume31
Issue number4
DOIs
StatePublished - Oct 2015

Keywords

  • Chronic pain symptoms
  • HIV/AIDS
  • He Din
  • Injection drug use
  • Palliative care
  • Prescription opioids

ASJC Scopus subject areas

  • Medicine(all)

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