Oxytocin labor stimulation of twin gestations

Effective and efficient

M. Bardett Fausett, William H. Barth, Bradley A. Yoder, Andrew Satin

Research output: Contribution to journalArticle

Abstract

Objective: To test the hypothesis that oxytocin labor stimulation of twin gestations is similar to that of singletons regarding dosage, time, complications, and ability to achieve vaginal delivery. Methods: This retrospective investigation included 124 gravidas receiving oxytocin for augmentation or induction of labor. Sixty-two women with twin gestations were matched by parity, cervical dilation at initiation of oxytocin, gestational age, oxytocin dosage regimen, and indications for oxytocin to controls with singleton pregnancies. Outcome variables included maximum dosage of oxytocin, incidence of hyperstimulation and fetal heart rate (FHR) abnormalities, time from oxytocin to delivery, cesarean deliveries, and maternal and neonatal outcomes. Statistical analysis was done using McNemar test, paired t test, and Wilcoxon signed-rank test for paired samples. Results: Women with twin pregnancies and those with singletons responded similarly regarding maximum oxytocin dosage (21 ± 1.5 and 18 ± 2.4 mU/minute, respectively, P = .1), time from oxytocin to delivery (7.0 ± 0.8 and 6.7 ± 0.6 hours, respectively, P = .88), and successful vaginal delivery (90% and 90%, respectively). Oxytocin stimulation of twins resulted in fewer interruptions of the infusion for FHR abnormalities (5% compared with 26%, odds ratio [OR] 0.27, 95% confidence interval [CI] 0.16, 0.47) and hyperstimulation (6% compared with 18%, OR 0.19, 95% CI 0.36, 0.99). Conclusion: Twin gestation has no adverse impact on the effectiveness or efficiency of oxytocin labor stimulation. Twin pregnancy seems to be associated with fewer side effects.

Original languageEnglish (US)
Pages (from-to)202-204
Number of pages3
JournalObstetrics and Gynecology
Volume90
Issue number2
DOIs
StatePublished - Aug 1997
Externally publishedYes

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Oxytocin
Pregnancy
Fetal Heart Rate
Twin Pregnancy
Congenital Heart Defects
Odds Ratio
Confidence Intervals
Induced Labor
Nonparametric Statistics
Parity
Gestational Age
Dilatation
Mothers

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Oxytocin labor stimulation of twin gestations : Effective and efficient. / Fausett, M. Bardett; Barth, William H.; Yoder, Bradley A.; Satin, Andrew.

In: Obstetrics and Gynecology, Vol. 90, No. 2, 08.1997, p. 202-204.

Research output: Contribution to journalArticle

Fausett, M. Bardett ; Barth, William H. ; Yoder, Bradley A. ; Satin, Andrew. / Oxytocin labor stimulation of twin gestations : Effective and efficient. In: Obstetrics and Gynecology. 1997 ; Vol. 90, No. 2. pp. 202-204.
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