TY - JOUR
T1 - Oximetric quantitation of intracardiac left-to-right shunting
T2 - Limitations of the Qp Qs ratio
AU - Cigarroa, Ricardo G.
AU - Lange, Richard A.
AU - Hillis, L. David
PY - 1989/7/15
Y1 - 1989/7/15
N2 - For over 40 years, analysis of the blood oxygen content in the right heart chambers has been used to detect and quantitate intracardiac left-to-right shunting.1 Using the Fick principle, pulmonary and systemic blood flows are calculated and then their ratio ( Qp Qs) is determined. Subsequently, numerous studies-including indicator dilution,2 radionuclide angiocardiography3,4 and Doppler echocardiography5,6-have used this ratio as the gold standard for measuring intracardiac left-to-right shunting, but its widespread use as such suggests an insufficient understanding of its potential inaccuracies. We performed this study to assess and quantitate the limitations of the Qp Qs ratio in patients with intracardiac left-to-right shunting.
AB - For over 40 years, analysis of the blood oxygen content in the right heart chambers has been used to detect and quantitate intracardiac left-to-right shunting.1 Using the Fick principle, pulmonary and systemic blood flows are calculated and then their ratio ( Qp Qs) is determined. Subsequently, numerous studies-including indicator dilution,2 radionuclide angiocardiography3,4 and Doppler echocardiography5,6-have used this ratio as the gold standard for measuring intracardiac left-to-right shunting, but its widespread use as such suggests an insufficient understanding of its potential inaccuracies. We performed this study to assess and quantitate the limitations of the Qp Qs ratio in patients with intracardiac left-to-right shunting.
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U2 - 10.1016/0002-9149(89)90471-2
DO - 10.1016/0002-9149(89)90471-2
M3 - Article
C2 - 2741836
AN - SCOPUS:0024400104
VL - 64
SP - 246
EP - 247
JO - American Journal of Cardiology
JF - American Journal of Cardiology
SN - 0002-9149
IS - 3
ER -