Oxidative degradation of testosterone by adaptive enzymes

Paul Talalay; Marie Mollomo Dobson; Donald F. Tapley

doi:10.1038/170620a0

Oxidative degradation of testosterone by adaptive enzymes

Paul Talalay, Marie Mollomo Dobson, Donald F. Tapley

School of Medicine

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Abstract

THE study of steroid synthesis by micro-organisms and certain oxidations and reductions of reactive groups at positions 3 and 17 of the steroid skeleton have been previously reported¹. Turfitt² has studied more extensive degradations of cholesterol by bacteria and has isolated products in which the side-chain has been removed and ring A opened. We should like to report the application of adaptive bacterial enzymes to the study of the oxidative degradation of steroid hormones.

Original language	English (US)
Pages (from-to)	620-621
Number of pages	2
Journal	Nature
Volume	170
Issue number	4328
DOIs	https://doi.org/10.1038/170620a0
State	Published - Dec 1 1952

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title = "Oxidative degradation of testosterone by adaptive enzymes",

abstract = "THE study of steroid synthesis by micro-organisms and certain oxidations and reductions of reactive groups at positions 3 and 17 of the steroid skeleton have been previously reported1. Turfitt2 has studied more extensive degradations of cholesterol by bacteria and has isolated products in which the side-chain has been removed and ring A opened. We should like to report the application of adaptive bacterial enzymes to the study of the oxidative degradation of steroid hormones.",

author = "Paul Talalay and Dobson, {Marie Mollomo} and Tapley, {Donald F.}",

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Oxidative degradation of testosterone by adaptive enzymes

Abstract

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