Oxidative degradation of testosterone by adaptive enzymes

Paul Talalay, Marie Mollomo Dobson, Donald F. Tapley

Research output: Contribution to journalArticle


THE study of steroid synthesis by micro-organisms and certain oxidations and reductions of reactive groups at positions 3 and 17 of the steroid skeleton have been previously reported1. Turfitt2 has studied more extensive degradations of cholesterol by bacteria and has isolated products in which the side-chain has been removed and ring A opened. We should like to report the application of adaptive bacterial enzymes to the study of the oxidative degradation of steroid hormones.

Original languageEnglish (US)
Pages (from-to)620-621
Number of pages2
Issue number4328
StatePublished - Dec 1 1952

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    Talalay, P., Dobson, M. M., & Tapley, D. F. (1952). Oxidative degradation of testosterone by adaptive enzymes. Nature, 170(4328), 620-621. https://doi.org/10.1038/170620a0