Abstract
Peroxidase, isolated from B16 mouse melanoma, converted tyrosine to dopachrome in the presence of either dopa or dihydroxyfumarate co-factor. A suspended homogenate of cloned, cultured B16 mouse melanoma cells also showed peroxidatic conversion of tyrosine to dopachrome in the presence of dihydroxyfumarate co-factor. The findings confirm previous histochemical, autoradiographic-histochemical, and EM-histochemical studies showing that melanoma peroxidase can convert tyrosine to melanin.
Original language | English (US) |
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Pages (from-to) | 8-12 |
Number of pages | 5 |
Journal | Physiological chemistry and physics |
Volume | 14 |
Issue number | 1 |
State | Published - 1982 |
Externally published | Yes |
ASJC Scopus subject areas
- General Medicine