Oxandrolone therapy in patients with Turnersyndrome

Maria D. Urban, Peter A. Lee, John P. Dorst, Leslie P. Plotnick, Claude J. Migeon

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Abstract

Long-term, low-dosage androgen treatment of patients with Turner syndrome results in more rapid growth and significantly greater adult height than in control patients who receive only estrogen for pubertal development. Seventeen patients treated with oxandrolone for one year and ten treated for two years had significantly greater growth velocities during than before treatment. Mean adult height of 25 patients treated with oxandrolone, fluoxymesterone, or both was significantly taller than the height of adult patients with Turner syndrome treated with estrogen only. Excessive skeletal maturation was not generally observed.

Original languageEnglish (US)
Pages (from-to)823-827
Number of pages5
JournalJournal of Pediatrics
Volume94
Issue number5
DOIs
Publication statusPublished - 1979

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Urban, M. D., Lee, P. A., Dorst, J. P., Plotnick, L. P., & Migeon, C. J. (1979). Oxandrolone therapy in patients with Turnersyndrome. Journal of Pediatrics, 94(5), 823-827. https://doi.org/10.1016/S0022-3476(79)80170-5