Overweight and obesity are increased in childhood-onset cerebrovascular disease

Virginia Pearson, Chris Ruzas, Nancy F. Krebs, Neil A. Goldenberg, Marilyn J. Manco-Johnson, Timothy J. Bernard

Research output: Contribution to journalArticlepeer-review

Abstract

The objective of this work was to determine whether overweight/obesity is a risk factor for cerebrovascular disease in children. The study included 53 children with non-neonatal-onset cerebral sinovenous thrombosis or arterial ischemic stroke. The prevalence of overweight/obesity was compared between this cohort and healthy children from the National Health and Nutrition Examination Survey. In addition, cerebral sinovenous thrombosis patients were compared to a group of matched hospitalized controls. The prevalence of overweight/obesity was significantly higher in the cerebral sinovenous thrombosis cohort (55%), but not the arterial ischemic stroke cohort (36%), relative to national controls (32%; P=.04 and P=.81, respectively). Similarly, the prevalence of overweight/obesity was significantly higher in the cerebral sinovenous thrombosis cohort than in Colorado controls (25%; P=.02). In conclusion, the prevalence of overweight/obese was significantly increased in cerebral sinovenous thrombosis patients as compared to both national and local controls. Results should be evaluated in a larger multi-institutional cohort.

Original languageEnglish (US)
Pages (from-to)517-519
Number of pages3
JournalJournal of child neurology
Volume28
Issue number4
DOIs
StatePublished - Apr 2013
Externally publishedYes

Keywords

  • arterial ischemic
  • cerebral sinovenous thrombosis
  • obesity
  • overweight
  • stroke

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

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