Overview of Therapeutic Drug Monitoring

William Clarke

doi:10.1016/B978-0-12-802025-8.00001-5

Overview of Therapeutic Drug Monitoring

William Clarke

School of Medicine

Research output: Chapter in Book/Report/Conference proceeding › Chapter

4 Scopus citations

Abstract

Therapeutic drug monitoring (TDM) is a key component of patient management for a select group of drugs that demonstrate significant interindividual variability in their pharmacokinetics and pharmacodynamics. Using pharmacokinetically guided dose adjustment is also a critical piece of personalized medicine in many cases. This chapter covers the emergence and key historical points of TDM, as well as important general concepts for TDM in clinical care.

Original language	English (US)
Title of host publication	Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions, and Pharmacogenomics
Publisher	Elsevier Inc.
Pages	1-15
Number of pages	15
ISBN (Electronic)	9780128020524
ISBN (Print)	9780128020258
DOIs	https://doi.org/10.1016/B978-0-12-802025-8.00001-5
State	Published - May 17 2016

Keywords

Dose adjustment
Interindividual variations
Personalized medicine
Pharmacokinetics
Therapeutic drug monitoring

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-802025-8.00001-5

Cite this

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AB - Therapeutic drug monitoring (TDM) is a key component of patient management for a select group of drugs that demonstrate significant interindividual variability in their pharmacokinetics and pharmacodynamics. Using pharmacokinetically guided dose adjustment is also a critical piece of personalized medicine in many cases. This chapter covers the emergence and key historical points of TDM, as well as important general concepts for TDM in clinical care.

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KW - Personalized medicine

KW - Pharmacokinetics

KW - Therapeutic drug monitoring

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PB - Elsevier Inc.

ER -

Overview of Therapeutic Drug Monitoring

Abstract

Keywords

ASJC Scopus subject areas

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