Overview of Therapeutic Drug Monitoring

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Therapeutic drug monitoring (TDM) is a key component of patient management for a select group of drugs that demonstrate significant interindividual variability in their pharmacokinetics and pharmacodynamics. Using pharmacokinetically guided dose adjustment is also a critical piece of personalized medicine in many cases. This chapter covers the emergence and key historical points of TDM, as well as important general concepts for TDM in clinical care.

Original languageEnglish (US)
Title of host publicationClinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions, and Pharmacogenomics
PublisherElsevier Inc.
Pages1-15
Number of pages15
ISBN (Electronic)9780128020524
ISBN (Print)9780128020258
DOIs
StatePublished - May 17 2016

Keywords

  • Dose adjustment
  • Interindividual variations
  • Personalized medicine
  • Pharmacokinetics
  • Therapeutic drug monitoring

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Clarke, W. (2016). Overview of Therapeutic Drug Monitoring. In Clinical Challenges in Therapeutic Drug Monitoring: Special Populations, Physiological Conditions, and Pharmacogenomics (pp. 1-15). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-802025-8.00001-5