Abstract
About 15% of reproductive aged couples in the United States experience infertility, which is defined as the failure to achieve a successful pregnancy after 12. months or more of appropriate, timed, and unprotected intercourse or therapeutic donor insemination. According to the American Society for Reproductive Medicine, about 30% of infertility cases can be attributed to female causes, 30% to male factors, and the remaining cases involve a combination of male and female factors, in addition to unexplained causes. Understanding the various pathologic mechanisms underlying infertility represents an active area of research and serves as an important first step in our ability to treat this health problem.
| Original language | English (US) |
|---|---|
| Title of host publication | Translational Cardiometabolic Genomic Medicine |
| Publisher | Elsevier Inc. |
| Pages | 251-282 |
| Number of pages | 32 |
| ISBN (Print) | 9780128004746, 9780127999616 |
| DOIs | |
| State | Published - Sep 14 2015 |
| Externally published | Yes |
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Keywords
- Cholesterol uptake
- HDL
- Infertility
- Metabolism
ASJC Scopus subject areas
- Medicine(all)
Cite this
Overview of the Intersection of Genomics of Cholesterol Metabolism and Cardiometabolic Disease with Reproductive Health, Especially in Women. / DeAngelis, Anthony M.; Roy-O'Reilly, Meaghan; Rodriguez-Oquendo, Annabelle.
Translational Cardiometabolic Genomic Medicine. Elsevier Inc., 2015. p. 251-282.Research output: Chapter in Book/Report/Conference proceeding › Chapter
}
TY - CHAP
T1 - Overview of the Intersection of Genomics of Cholesterol Metabolism and Cardiometabolic Disease with Reproductive Health, Especially in Women
AU - DeAngelis, Anthony M.
AU - Roy-O'Reilly, Meaghan
AU - Rodriguez-Oquendo, Annabelle
PY - 2015/9/14
Y1 - 2015/9/14
N2 - About 15% of reproductive aged couples in the United States experience infertility, which is defined as the failure to achieve a successful pregnancy after 12. months or more of appropriate, timed, and unprotected intercourse or therapeutic donor insemination. According to the American Society for Reproductive Medicine, about 30% of infertility cases can be attributed to female causes, 30% to male factors, and the remaining cases involve a combination of male and female factors, in addition to unexplained causes. Understanding the various pathologic mechanisms underlying infertility represents an active area of research and serves as an important first step in our ability to treat this health problem.
AB - About 15% of reproductive aged couples in the United States experience infertility, which is defined as the failure to achieve a successful pregnancy after 12. months or more of appropriate, timed, and unprotected intercourse or therapeutic donor insemination. According to the American Society for Reproductive Medicine, about 30% of infertility cases can be attributed to female causes, 30% to male factors, and the remaining cases involve a combination of male and female factors, in addition to unexplained causes. Understanding the various pathologic mechanisms underlying infertility represents an active area of research and serves as an important first step in our ability to treat this health problem.
KW - Cholesterol uptake
KW - HDL
KW - Infertility
KW - Metabolism
UR - http://www.scopus.com/inward/record.url?scp=84967221254&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84967221254&partnerID=8YFLogxK
U2 - 10.1016/B978-0-12-799961-6.00011-1
DO - 10.1016/B978-0-12-799961-6.00011-1
M3 - Chapter
AN - SCOPUS:84967221254
SN - 9780128004746
SN - 9780127999616
SP - 251
EP - 282
BT - Translational Cardiometabolic Genomic Medicine
PB - Elsevier Inc.
ER -