TY - JOUR
T1 - Overview of animal models of asthma.
AU - Canning, Brendan J.
PY - 2002/5/1
Y1 - 2002/5/1
N2 - Asthma is an inflammatory disease characterized by airways obstruction, airways hyperresponsiveness, excessive mucous secretion and cough. Guinea pig airways display many anatomical, physiological and pharmacological attributes of human airways, making this species ideal for modeling the asthmatic condition. This unit provides an overview of animal models of asthma, including definitions, descriptions of available animal models, and discussion of numerous critical issues to consider before designing a model to study this complex disease.
AB - Asthma is an inflammatory disease characterized by airways obstruction, airways hyperresponsiveness, excessive mucous secretion and cough. Guinea pig airways display many anatomical, physiological and pharmacological attributes of human airways, making this species ideal for modeling the asthmatic condition. This unit provides an overview of animal models of asthma, including definitions, descriptions of available animal models, and discussion of numerous critical issues to consider before designing a model to study this complex disease.
UR - http://www.scopus.com/inward/record.url?scp=84858846800&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84858846800&partnerID=8YFLogxK
U2 - 10.1002/0471141755.ph0525s16
DO - 10.1002/0471141755.ph0525s16
M3 - Article
C2 - 22294076
AN - SCOPUS:84858846800
SN - 1934-8282
VL - Chapter 5
SP - Unit 5.25
JO - Current protocols in pharmacology / editorial board, S.J. Enna (editor-in-chief) ... [et al.]
JF - Current protocols in pharmacology / editorial board, S.J. Enna (editor-in-chief) ... [et al.]
ER -