Overview, Description, and Types of Sleep-Related Breathing Disorders

S. P. Patil, Jason Kirkness

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Sleep-related breathing disorders (SRBDs) encompass a collection of disorders that include obstructive sleep apnea syndromes, central sleep apnea syndromes, and sleep-related hypoventilation/hypoxemic syndromes. SRBDs result in periods of hypoventilation, which can result in gas exchange abnormalities (e.g., hypercapnia/hypoxemia) and recurrent arousals from sleep. Recurrent periods of hypoventilation may then set offa cascade of additional physiologic sequelae including sympathetic activation, inflammation, endothelial dysfunction, metabolic dysregulation, and recurrent blood pressure swings that are associated with clinical sequelae of hypertension, cardiovascular disease, neurocognitive impairment, glucose intolerance, and early mortality. Diagnoses of SRBDs typically require polysomnography. In this article, a broad overview and description of the varying SRBDs will be reviewed.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Sleep
PublisherElsevier Inc.
Pages222-231
Number of pages10
ISBN (Electronic)9780123786111
ISBN (Print)9780123786104
DOIs
StatePublished - Jan 1 2013

Keywords

  • Apnea
  • Central sleep apnea
  • Cheyne-Stokes respiration
  • Hypopnea
  • Hypoventilation syndromes
  • Obstructive sleep apnea
  • Respiratory effort-related arousals

ASJC Scopus subject areas

  • Medicine (miscellaneous)

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