TY - JOUR
T1 - Overlapping neurobehavioral circuits in ADHD, obesity, and binge eating
T2 - Evidence from neuroimaging research
AU - Seymour, Karen E.
AU - Reinblatt, Shauna P.
AU - Benson, Leora
AU - Carnell, Susan
N1 - Publisher Copyright:
© 2015 Cambridge University Press.
PY - 2015
Y1 - 2015
N2 - Attention-deficit/hyperactivity disorder (ADHD) and conditions involving excessive eating (eg, obesity, binge/loss of control eating) are increasingly prevalent within pediatric populations, and correlational and some longitudinal studies have suggested inter-relationships between these disorders. In addition, a number of common neural correlates are emerging across conditions, eg, functional abnormalities within circuits subserving reward processing and executive functioning. To explore this potential cross-condition overlap in neurobehavioral underpinnings, we selectively review relevant functional neuroimaging literature, specifically focusing on studies probing (i) reward processing, (ii) response inhibition, and (iii) emotional processing and regulation, and we outline 3 specific shared neurobehavioral circuits. Based on our review, we also identify gaps within the literature that would benefit from further research.
AB - Attention-deficit/hyperactivity disorder (ADHD) and conditions involving excessive eating (eg, obesity, binge/loss of control eating) are increasingly prevalent within pediatric populations, and correlational and some longitudinal studies have suggested inter-relationships between these disorders. In addition, a number of common neural correlates are emerging across conditions, eg, functional abnormalities within circuits subserving reward processing and executive functioning. To explore this potential cross-condition overlap in neurobehavioral underpinnings, we selectively review relevant functional neuroimaging literature, specifically focusing on studies probing (i) reward processing, (ii) response inhibition, and (iii) emotional processing and regulation, and we outline 3 specific shared neurobehavioral circuits. Based on our review, we also identify gaps within the literature that would benefit from further research.
KW - Attention-deficit/hyperactivity disorder
KW - comorbidity
KW - fMRI
KW - obesity
KW - overweight
UR - http://www.scopus.com/inward/record.url?scp=84938751808&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84938751808&partnerID=8YFLogxK
U2 - 10.1017/S1092852915000383
DO - 10.1017/S1092852915000383
M3 - Review article
C2 - 26098969
AN - SCOPUS:84938751808
SN - 1092-8529
VL - 20
SP - 401
EP - 411
JO - CNS spectrums
JF - CNS spectrums
IS - 4
ER -