Ovarian cancer in elderly women

Nicholas C. Lambrou, Robert E. Bristow

Research output: Contribution to journalReview article

Abstract

The incidence of ovarian carcinoma increases with advancing age, peaking during the 7th decade of life and remaining elevated until age 80 years. Despite the high prevalence of ovarian cancer in the elderly, the management of these patients is often less aggressive than that of their younger counterparts. As a result, many elderly cancer patients receive inadequate treatment. However, data do not support the concept that age, perse, is a negative prognostic factor. In fact, the maJority of elderly patients are able to tolerate the standard of care for ovarian cancer including initial surgical cytoreduction followed by platinum and taxane chemotherapy. Because functional status has not demonstrated a reliable correlation with either tumor stage or comorbidity, each patient's comorbidities should be assessed independently. For elderly patients with significant medical comorbidity, the extent of surgery and aggressiveness of chemotherapy should be tailored to the extent of disease, symptoms, overall health, and life goals. In addition, enhanced cooperation between geriatricians and oncologists may assist the pre treatment assessment of elderly patients and improve treatment guidelines in this population.

Original languageEnglish (US)
Pages (from-to)1075-1081
Number of pages7
JournalONCOLOGY
Volume17
Issue number8
StatePublished - Aug 1 2003

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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    Lambrou, N. C., & Bristow, R. E. (2003). Ovarian cancer in elderly women. ONCOLOGY, 17(8), 1075-1081.