TY - JOUR
T1 - Outcomes of universal access to antiretroviral therapy (ART) in Georgia
AU - Tsertsvadze, Tengiz
AU - Chkhartishvili, Nikoloz
AU - Sharvadze, Lali
AU - Dvali, Natia
AU - Chokoshvili, Otar
AU - Gabunia, Pati
AU - Abutidze, Akaki
AU - Nelson, Kenrad
AU - Dehovitz, Jack
AU - Del Rio, Carlos
PY - 2011
Y1 - 2011
N2 - Since 2004, Georgia achieved universal access to free antiretroviral therapy (ART). A retrospective cohort study was conducted to evaluate the outcomes of Georgia's ART program. The study included adult patients enrolled in the ART program from 2004 through 2009. Of 752 patients, 76% were men, 60% were injection drug users (IDU), 59% had a history of an AIDS-defining illness, and 53% were coinfected with hepatitis C. The median baseline CD4 cell count was 141 cells/mm3. During followup, 152 (20%) patients died, with the majority of deaths occurring within 12 months of ART initiation. Mortality was associated with advanced immunodeficiency or the presence of incurable disease at baseline. Among patients remaining on treatment, the median CD4 gain was 216 cell/mm3 and 86% of patients had viral load <400 copies/ml at the last clinical visit. The Georgia ART program has been successful in treating injection drug users infected with HIV.
AB - Since 2004, Georgia achieved universal access to free antiretroviral therapy (ART). A retrospective cohort study was conducted to evaluate the outcomes of Georgia's ART program. The study included adult patients enrolled in the ART program from 2004 through 2009. Of 752 patients, 76% were men, 60% were injection drug users (IDU), 59% had a history of an AIDS-defining illness, and 53% were coinfected with hepatitis C. The median baseline CD4 cell count was 141 cells/mm3. During followup, 152 (20%) patients died, with the majority of deaths occurring within 12 months of ART initiation. Mortality was associated with advanced immunodeficiency or the presence of incurable disease at baseline. Among patients remaining on treatment, the median CD4 gain was 216 cell/mm3 and 86% of patients had viral load <400 copies/ml at the last clinical visit. The Georgia ART program has been successful in treating injection drug users infected with HIV.
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U2 - 10.1155/2011/621078
DO - 10.1155/2011/621078
M3 - Article
C2 - 21490781
AN - SCOPUS:84861013972
SN - 2090-1240
VL - 2011
JO - AIDS Research and Treatment
JF - AIDS Research and Treatment
M1 - 621078
ER -