Outcomes from acute attacks of neuromyelitis optica spectrum disorder correlate with severity of attack, age and delay to treatment

Aditya Banerjee, Jennifer Ng, Jessica Coleman, Juan Pablo Ospina, Maureen Mealy, Michael Levy

Research output: Contribution to journalArticlepeer-review

Abstract

Neuromyelitis optica spectrum disorder (NMOSD) attacks lead to incremental loss of function of the optic nerves and spinal cord. The standard of care for treatment of acute attacks to mitigate damage is high dose corticosteroids and, if needed, plasma exchange. Although the inclination among clinicians is to treat relapses as soon as they start, there is no previously published evidence to conclude that earlier treatment with corticosteroids is more effective in the long term. In this study, we correlated neurological outcomes from acute NMOSD relapses with delay to treatment, as well as demographic and clinical characteristics that influence prognosis.

Original languageEnglish (US)
Pages (from-to)60-63
Number of pages4
JournalMultiple Sclerosis and Related Disorders
Volume28
DOIs
StatePublished - Feb 2019

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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