Other Secondary Hyperparathyroid States

Laila Tabatabai, Suzanne M. Jan De Beur

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Parathyroid hormone (PTH) secretion is regulated by a complex interplay of circulating minerals and hormones that include extracellular calcium (via the calcium-sensing receptor, CaSR), plasma phosphate, 1,25-dihydroxyvitamin D (1,25(OH)2D), and fibroblast growth factor 23 (FGF23). The most common causes of secondary hyperparathyroidism are renal disease and vitamin D deficiency. Although less common, other conditions that cause secondary hyperparathyroidism include disorders of calcium balance (deficiency, malabsorption, and excess excretion), disorders associated with FGF23 excess, persistent parathyroid disease after renal transplant, specific disorders of acid-base balance, and ingestion of certain medications.

Original languageEnglish (US)
Title of host publicationThe Parathyroids
Subtitle of host publicationBasic and Clinical Concepts: Third Edition
PublisherElsevier Inc.
Pages671-684
Number of pages14
ISBN (Print)9780123971661
DOIs
StatePublished - Jan 1 2015

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Keywords

  • Autosomal dominant hypophosphatemic rickets (ADHR)
  • Bone mineral density (BMD)
  • Calcium
  • Calcium-phosphate balance
  • Fibroblast growth factor 23 (FGF23)
  • Hypercalciuria
  • Rickets
  • Tumor-induced osteomalacia (TIO)

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Tabatabai, L., & Jan De Beur, S. M. (2015). Other Secondary Hyperparathyroid States. In The Parathyroids: Basic and Clinical Concepts: Third Edition (pp. 671-684). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-397166-1.00046-1